Evidence map›Paper›PMID 36413523›Full record

ArticlePLoS computational biology2022

Look twice: A generalist computational model predicts return fixations across tasks and species.

Mengmi Zhang, Marcelo Armendariz, Will Xiao, Olivia Rose, Katarina Bendtz, Margaret Livingstone, Carlos Ponce, Gabriel Kreiman

Open access · goldAbstract read
In one paragraph

Article in PLoS computational biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Motor "laziness" constrains fixation selection in real-world tasks.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Inactivation of face-selective neurons alters eye movements when free viewing faces.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Visual Search Asymmetry: Deep Nets and Humans Share Similar Inherent Biases.Advances in neural information processing systems · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Mengmi ZhangBoston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0002-2694-7097
Marcelo ArmendarizBoston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0002-7905-1104
Will XiaoDepartment of Neurobiology, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0001-5555-3217
Olivia RoseDepartment of Neurobiology, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0003-1762-2829
Katarina BendtzBoston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Margaret LivingstoneDepartment of Neurobiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Carlos PonceDepartment of Neurobiology, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0002-9887-3234
Gabriel KreimanBoston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0003-3505-8475
Harvard University · USBoston Children's Hospital · USAgency for Science, Technology and Research · SG

Funding

Viral ModuleP30EY012196 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Gabriel Kreiman · 1998 to 2026
$21.3M
Reverse Correlation Mapping in V2 and V4R01EY016187 · NEI · HARVARD MEDICAL SCHOOL · PI LIVINGSTONE, MARGARET S · 2006 to 2021
$7.9M
Neural dynamics underlying spatiotemporal cognitive integrationR01EY026025 · NEI · BOSTON CHILDREN'S HOSPITAL · PI KREIMAN, GABRIEL · 2016 to 2024
$3.7M
NEI NIH HHS P30 EY012196NEI NIH HHS R01 EY016187NEI NIH HHS R01 EY026025
6 · The paper itself

Abstract

Primates constantly explore their surroundings via saccadic eye movements that bring different parts of an image into high resolution. In addition to exploring new regions in the visual field, primates also make frequent return fixations, revisiting previously foveated locations. We systematically studied a total of 44,328 return fixations out of 217,440 fixations. Return fixations were ubiquitous across different behavioral tasks, in monkeys and humans, both when subjects viewed static images and when subjects performed natural behaviors. Return fixations locations were consistent across subjects, tended to occur within short temporal offsets, and typically followed a 180-degree turn in saccadic direction. To understand the origin of return fixations, we propose a proof-of-principle, biologically-inspired and image-computable neural network model. The model combines five key modules: an image feature extractor, bottom-up saliency cues, task-relevant visual features, finite inhibition-of-return, and saccade size constraints. Even though there are no free parameters that are fine-tuned for each specific task, species, or condition, the model produces fixation sequences resembling the universal properties of return fixations. These results provide initial steps towards a mechanistic understanding of the trade-off between rapid foveal recognition and the need to scrutinize previous fixation locations.

Indexed as

Fixation, OcularSaccadesAnimalsCuesHumansPrimatesVisual Fields

Identifiers

PMID36413523
PMCPMC9681066
OpenAlexW4309621478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.