Evidence map›Paper›PMID 36413377›Full record

ArticleAmerican journal of respiratory cell and molecular biology2024

LungMAP Portal Ecosystem: Systems-level Exploration of the Lung.

Nathan Gaddis, Joshua Fortriede, Minzhe Guo, Eric E Bardes, Michal Kouril, Scott Tabar, Kevin Burns, Maryanne E Ardini-Poleske, Stephanie Loos, Daniel Schnell and 25 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Genetic susceptibility to PMFrontiers in immunology · 2026
    Article
  15. Article
  16. Review
  17. Correspondence regarding: Lung organoids: a new frontier in neonatology and paediatric respiratory medicine.European respiratory review : an official journal of the European Respiratory Society · 2026
    Article
  18. Endothelial Heterogeneity in Pulmonary Hypertension.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors at 11 institutions in 2 countries.

Nathan GaddisRTI International, Research Triangle Park, North Carolina.
Joshua FortriedeDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Minzhe GuoDivision of Pulmonary Biology, The Perinatal Institute, and.
Eric E BardesDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Michal KourilDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Scott TabarDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Kevin BurnsDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Maryanne E Ardini-PoleskeRTI International, Research Triangle Park, North Carolina.
Stephanie LoosDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Daniel SchnellDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Kang JinDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Balaji IyerDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Yina DuDivision of Pulmonary Biology, The Perinatal Institute, and.
Bing-Xing HuoData Sciences Platform, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Anukana BhattacharjeeDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Jeff KorteData Sciences Platform, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Ruchi MunshiData Sciences Platform, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Victoria SmithData Sciences Platform, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Andrew HerbstData Sciences Platform, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Joseph A KitzmillerDivision of Pulmonary Biology, The Perinatal Institute, and.
Geremy C ClairBiological Science Division, Pacific Northwest National Laboratory, Richland, Washington.ORCID 0000-0003-0478-8520
James P CarsonTexas Advanced Computing Center, University of Texas at Austin, Austin, Texas.
Joshua AdkinsBiological Science Division, Pacific Northwest National Laboratory, Richland, Washington.
Edward E MorriseyDepartment of Medicine and.
Gloria S PryhuberDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York.ORCID 0000-0002-9185-3994
Ravi MisraDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York.
Jeffrey A WhitsettDivision of Pulmonary Biology, The Perinatal Institute, and.
Xin SunDepartment of Pediatrics and.
Trevor HeathornUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, California.
Benedict PatenUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, California.
V B Surya PrasathDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Yan XuDivision of Pulmonary Biology, The Perinatal Institute, and.
Tim TickleData Sciences Platform, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Bruce J AronowDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Nathan SalomonisDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0001-9689-2469
Cincinnati Children's Hospital Medical Center · USBroad Institute · USPacific Northwest National Laboratory · USPerinatal Institute · GBUniversity of California, Santa Cruz · USUniversity of Rochester Medical Center · USEarthTech International (United States) · USResearch Triangle Park Foundation · USRTI International · USUniversity of California San Diego · USUniversity of Pennsylvania · US

Funding

The AnVIL Data Ecosystem DACReS SupplementU24HG010262 · NHGRI · BROAD INSTITUTE, INC. · PI Robert J Carroll, Jonathan Lawson · 2018 to 2026
$40.5M
The WashU-UCSC-EBI Human Genome Reference Center."U41HG010972 · NHGRI · WASHINGTON UNIVERSITY · PI Ira M Hall, Heng Li · 2019 to 2026
$24.9M
The LungMAP Data Coordination Center for Next Gen Systems Biology of RespirationU24HL148865 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Bruce J Aronow, Nathan G. Salomonis · 2019 to 2026
$12.4M
BioRepository for INvestigation of Diseases of the Lung (BRINDL) - Phase IIIU01HL148861 · NHLBI · UNIVERSITY OF ROCHESTER · PI GLORIA S PRYHUBER · 2019 to 2026
$9.7M
The Human Lung BioMolecular Multi-Scale Atlas Program (HuBMAP-Lung)U54HL165443 · NHLBI · UNIVERSITY OF ROCHESTER · PI PRYHUBER, GLORIA S · 2022 to 2025
$8.0M
Biorepository for Investigation of Neonatal Diseases of Lung-Normal (BRINDL-NL)U01HL122700 · NHLBI · UNIVERSITY OF ROCHESTER · PI PRYHUBER, GLORIA S · 2014 to 2018
$6.1M
Dockstore: The Community Platform for Reproducible Biomedical Workflows and ApplicationsU24HG011853 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Jonathan Lawson, Benedict Paten · 2021 to 2026
$5.7M
Research Center for Spatiotemporal Lung Imaging and OmicsU01HL148860 · NHLBI · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI ADKINS, JOSHUA N., CARSON, JAMES PAUL · 2019 to 2023
$4.7M
LungMap Phase II - Building a multidimensional map of developing human lungU01HL148856 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI WHITSETT, JEFFREY A, XU, YAN · 2019 to 2023
$4.5M
Multi-modal characterization of three human lung niches at the single cell levelU01HL148857 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MORRISEY, EDWARD E · 2019 to 2023
$4.4M
Decoding the Cellular Niches Critical for Lung Maturation and PathogenesisU01HL148867 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUN, XIN · 2019 to 2023
$4.4M
Uterine signaling networks in the pathogenesis of pulmonary lymphangioleiomyomatosis (LAM)R01HL153045 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI XU, YAN, YU, JANE · 2020 to 2023
$3.1M
NHGRI NIH HHS R01 HG010485NHGRI NIH HHS U24 HG010262NHGRI NIH HHS U24 HG011853NHGRI NIH HHS U41 HG010972NHLBI NIH HHS R01 HL153045NHLBI NIH HHS U01 HL122700NHLBI NIH HHS U01HL122700NHLBI NIH HHS U01 HL148856NHLBI NIH HHS U01HL148856NHLBI NIH HHS U01 HL148857NHLBI NIH HHS U01HL148857NHLBI NIH HHS U01 HL148860NHLBI NIH HHS U01HL148860NHLBI NIH HHS U01 HL148861NHLBI NIH HHS U01HL148861NHLBI NIH HHS U01 HL148867NHLBI NIH HHS U01HL148867NHLBI NIH HHS U01 HL175383NHLBI NIH HHS U24 HL148865NHLBI NIH HHS U24HL148865NHLBI NIH HHS U54 HL165443
6 · The paper itself

Abstract

An improved understanding of the human lung necessitates advanced systems models informed by an ever-increasing repertoire of molecular omics, cellular imaging, and pathological datasets. To centralize and standardize information across broad lung research efforts, we expanded the LungMAP.net website into a new gateway portal. This portal connects a broad spectrum of research networks, bulk and single-cell multiomics data, and a diverse collection of image data that span mammalian lung development and disease. The data are standardized across species and technologies using harmonized data and metadata models that leverage recent advances, including those from the Human Cell Atlas, diverse ontologies, and the LungMAP CellCards initiative. To cultivate future discoveries, we have aggregated a diverse collection of single-cell atlases for multiple species (human, rhesus, and mouse) to enable consistent queries across technologies, cohorts, age, disease, and drug treatment. These atlases are provided as independent and integrated queryable datasets, with an emphasis on dynamic visualization, figure generation, reanalysis, cell-type curation, and automated reference-based classification of user-provided single-cell genomics datasets (Azimuth). As this resource grows, we intend to increase the breadth of available interactive interfaces, supported data types, data portals and datasets from LungMAP, and external research efforts.

Indexed as

GenomicsAnimalsHumansLungMammalsMiceOrganogenesisgenomicshuman cell atlasLungMAPproteomicssingle-cell atlas

Identifiers

PMID36413377
PMCPMC10848697
OpenAlexW4309663642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.