Evidence map›Paper›PMID 36413338›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2023

Spectrum and mortality of opportunistic infections among HIV/AIDS patients in southwestern China.

Sirun Meng, Qiao Tang, Zhiman Xie, Nianning Wu, Yingmei Qin, Rongfeng Chen, Xiaoyu Chen, Xiu Chen, Yueqi Li, Minjuan Shi and 5 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  7. Article
  8. Article
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  10. Evolving Disease Spectrum and Characteristics of People with HIV in Eastern China: A 12-Year Study.Mediterranean journal of hematology and infectious diseases · 2025
    Article
  11. Article
  12. Article
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  19. Coinfections and In-Hospital Mortality in a Group of Patients With HIV/AIDS: A Longitudinal Study.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Sirun Meng *The Fourth People's Hospital of Nanning, Nanning, 530023, Guangxi, China.
Qiao Tang *Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Zhiman XieThe Fourth People's Hospital of Nanning, Nanning, 530023, Guangxi, China.
Nianning WuThe Fourth People's Hospital of Nanning, Nanning, 530023, Guangxi, China.
Yingmei QinThe Fourth People's Hospital of Nanning, Nanning, 530023, Guangxi, China.
Rongfeng ChenGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Xiaoyu ChenThe Fourth People's Hospital of Nanning, Nanning, 530023, Guangxi, China.
Xiu ChenGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Yueqi LiJoint Laboratory for Emerging Infections Diseases in China (Guangxi)-ASEAN, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
Minjuan ShiGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Li YeGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Hao LiangJoint Laboratory for Emerging Infections Diseases in China (Guangxi)-ASEAN, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
Junjun JiangThe Fourth People's Hospital of Nanning, Nanning, 530023, Guangxi, China. jiangjunjun@gxmu.edu.cn.ORCID http://orcid.org/0000-0003-4905-9348
Bo ZhouGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, 530021, Guangxi, China. gxzhoubo520@126.com.
Jianyan LinThe Fourth People's Hospital of Nanning, Nanning, 530023, Guangxi, China. linjianyan@126.com.
Guangxi Medical University · CNThe Fourth People's Hospital · CNGuangxi University · CN

Funding

Guangxi Key Research and Development Plan Guike AB18050022Guangxi Science Fund for Distinguished Young Scholars 2018GXNSFFA281001Nanning Science and Technology Major Project 20193008National Natural Science Foundation of China 81971934Self-financed Programs of Health Commission of Guangxi Z20210498
6 · The paper itself

Abstract

We describe the opportunistic infections (OIs) of HIV/AIDS to understand the spectrum, mortality, and frequency of multiple coinfected OIs among HIV/AIDS patients in southern China, where OIs are severe. We carried out a retrospective cohort study of hospitalized HIV-infected individuals at the Fourth People's Hospital of Nanning, Guangxi, China, from Jan. 2011 to May. 2019. The chi-square test was used to analyze cross-infection; the Kaplan‒Meier analysis was used to compare mortality. A total of 12,612 HIV-infected patients were admitted to this cohort study. Among them, 8982 (71.2%) developed one or more OIs. The overall in-hospital mortality rate was 9.0%. Among the patients, 35.6% coinfected one OI, and 64.4% coinfected more than two OIs simultaneously. Almost half of the patients (60.6%) had CD4 + T-cell counts < 200 cells/μL. Pneumonia (39.8%), tuberculosis (35.3%), and candidiasis (28.8%) were the most common OIs. Coinfected cryptococcal meningitis and dermatitis are the most common combined OIs. The rate of anaemia (17.0%) was highest among those common HIV-associated complications. Multiple OIs are commonly found in hospitalized HIV/AIDS patients in southwestern China, which highlights the need for improved diagnosis and treatment.

Indexed as

Acquired Immunodeficiency SyndromeAIDS-Related Opportunistic InfectionsCoinfectionHIV InfectionsCD4 Lymphocyte CountChinaCohort StudiesHumansRetrospective StudiesHIV/AIDSMortalityOpportunistic infectionsSouthwestern ChinaSpectrum

Identifiers

PMID36413338
PMCPMC9816182
OpenAlexW4309666801

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.