Evidence map›Paper›PMID 36412985›Full record

ArticleCell cycle (Georgetown, Tex.)2023

Long non-coding RNA NCK1-AS1 functions as a ceRNA to regulate cell viability and invasion in esophageal squamous cell carcinoma via microRNA-133b/ENPEP axis.

Xiang-Yuan He, Xiu-Qi Wang, Qi-Lu Xiao, Duan Liu, Qi-Rong Xu, Sheng Liu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiang-Yuan HeDepartment of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, P. R. China.
Xiu-Qi WangDepartment of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, P. R. China.
Qi-Lu XiaoDepartment of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, P. R. China.
Duan LiuDepartment of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, P. R. China.
Qi-Rong XuDepartment of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, P. R. China.
Sheng LiuDepartment of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, P. R. China.
First Affiliated Hospital of Nanchang University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is designed to explore the role of long non-coding RNAs (lncRNAs) NCK1-AS1 in proliferative and invasive activities of esophageal squamous cell carcinoma (ESCC) cells by binding to microRNA-133b (miR-133b) to regulate ENPEP. Differentially expressed lncRNAs, miRs, genes and their targeting relationships were screened on ESCC-related gene expression datasets GSE17351 and GSE6188. The targeting relationships among NCK1-AS1, miR-133b, and ENPEP were verified using functional assays. Loss- and gain- of function assays were carried out to examine the roles of NCK1-AS1, miR-133b, and ENPEP in ESCC cell proliferative, invasive, migrative and apoptotic abilities as well as tumorigenesis

Indexed as

Esophageal NeoplasmsEsophageal Squamous Cell CarcinomaMicroRNAsRNA, Long NoncodingCarcinogenesisCell Line, TumorCell MovementCell ProliferationCell SurvivalGene Expression Regulation, NeoplasticHumansMicroRNAsRNA, Long Noncodingesophageal squamous cell carcinomaglutamyl aminopeptidaseinvasionLong noncoding RNA NCK1-AS1microRNA-133bmigrationviability

Identifiers

PMID36412985
PMCPMC9928473
OpenAlexW4309573964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.