Evidence map›Paper›PMID 36412861›Full record

ArticleJournal of functional biomaterials2022

Preparation and Characterization of a Polyetherketoneketone/Hydroxyapatite Hybrid for Dental Applications.

Wenhsuan Lu, Conglei Li, Jian Wu, Zhongshi Ma, Yadong Zhang, Tianyi Xin, Xiaomo Liu, Si Chen

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenhsuan LuDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, China.
Conglei LiAdvanced Materials Division, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China.
Jian WuAdvanced Materials Division, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China.
Zhongshi MaAdvanced Materials Division, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China.
Yadong ZhangAdvanced Materials Division, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China.
Tianyi XinDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, China.
Xiaomo LiuDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, China.
Si ChenDepartment of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, China.

Funding

Natural Science Foundation of Jiangxi Province of China 20192ACB20033Ningxia Hui Autonomous Region key Research and Development program 2022BEG02031Open Funding of NMPA Key Laboratory for Dental Materials PKUSS-20190401Peking University Medicine Fund of Fostering Young Scholars' Scientific and Techno-logical Innovation BMU2022PYB027Program for New Clinical Techniques and Therapies of Peking University School and Hospital of Stomatology PKUSSNCT-20B04Program for New Clinical Techniques and Therapies of Peking University School and Hospital of Stomatology PKUSSNCT-21B11Project funded by China Postdoctoral Science Foundation 2021M700282Research Foundation of Peking University School and Hospital of Stomatology PKUSS20210101the National Natural Science Foundation of China 52063030
6 · The paper itself

Abstract

Here, we developed a new synthetic method for the production of a new class of polymeric inorganic hybrid biomaterial that has potential for dental implant applications and, in general, other orthopedic applications owing to its excellent mechanical properties and biomechanical compatibility. The new hybrid biomaterial is a composite consisting of polyetherketoneketone (PEKK) and hydroxyapatite (HA). This hybrid material boasts several unique features, including its high HA loading (up to 50 wt%), which is close to that of natural human bone; the homogeneous HA distribution in the PEKK matrix without phase separation; and the fact that the addition of HA has no effect on the molecular weight of PEKK. Nanoindentation analysis was used to investigate the mechanical properties of the composite, and its nano/microstructure variations were investigated through a structural model developed here. Through nanoindentation technology, the newly developed PEKK/HA hybrid biomaterial has an indentation modulus of 12.1 ± 2.5 GPa and a hardness of 0.42 ± 0.09 GPa, which are comparable with those of human bone. Overall, the new PEKK/HA biomaterial exhibits excellent biomechanical compatibility and shows great promise for application to dental and orthopedic devices.

Indexed as

compositedentalhigh performancehybridhydroxyapatitemechanical compatibilityorthodonticorthopedicpolyetherketoneketone

Identifiers

PMID36412861
PMCPMC9680429

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.