Evidence map›Paper›PMID 36412598›Full record

ReviewDiseases (Basel, Switzerland)2022

Measles Induced Encephalitis: Recent Interventions to Overcome the Obstacles Encountered in the Management Amidst the COVID-19 Pandemic.

Mufaddal Najmuddin Diwan, Saba Samad, Rabeea Mushtaq, Alifiya Aamir, Zoha Allahuddin, Irfan Ullah, Rifayat Ullah Afridi, Aneela Ambreen, Adel Khan, Nimra Ehsan and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Mufaddal Najmuddin DiwanDow Medical College, Karachi 75700, Pakistan.
Saba SamadDow Medical College, Karachi 75700, Pakistan.
Rabeea MushtaqDow Medical College, Karachi 75700, Pakistan.
Alifiya AamirDow Medical College, Karachi 75700, Pakistan.
Zoha AllahuddinDow Medical College, Karachi 75700, Pakistan.
Irfan UllahDepartment of Pediatrics, Naseer Teaching Hospital, Peshawar 25120, Pakistan.ORCID 0000-0003-1100-101X
Rifayat Ullah AfridiDepartment of Pediatrics, Naseer Teaching Hospital, Peshawar 25120, Pakistan.
Aneela AmbreenDepartment of Pediatrics, Naseer Teaching Hospital, Peshawar 25120, Pakistan.
Adel KhanKhyber Medical College, Peshawar 25120, Pakistan.
Nimra EhsanKhyber Medical College, Peshawar 25120, Pakistan.
Zoia Ehsan KhattakKhyber Medical College, Peshawar 25120, Pakistan.
Antonio VentriglioDepartment of Psychiatry, University of Foggia, 71121 Foggia, Italy.ORCID 0000-0002-3934-7007
Domenico De BerardisDepartment of Psychiatry, Azienda Sanitaria Locale 4, 64100 Teramo, Italy.ORCID 0000-0003-4415-5058
Dow University of Health Sciences · PKKhyber Medical College · PKKhyber Teaching Hospital · PKUniversity of Foggia · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Encephalitis, a well-known complication of measles, is inflammation of the brain parenchyma which is mostly due to the viral invasion of neurons. It presents with a variety of symptoms ranging from mild to severe depending on the extent of the damaged neurons. The diagnosis is based on clinical symptoms such as fever, headache, altered level of consciousness, focal neurological deficits, etc. A detailed history and physical examination facilitate the diagnosis. Investigations include blood tests for measles-specific antibodies, CT, MRI, and analysis of the CSF. The management of measles-induced encephalitis mainly revolves around prevention against contracting the disease and providing supportive care if acquired. The administration of the measles vaccine is the major means of preventing this disease in childhood. Two doses are required to achieve sufficient immunity against measles, the first at the age of 12-15 months and the second at 4-6 years of age. Supportive care includes administering acetaminophen for fever, oral rehydrating salt (ORS) for diarrhea and vomiting, antibiotics for otitis media and pneumonia, and using anti-epileptics such as sodium valproate for seizures. Vitamin A can be given to prevent severe effects in children. The specific treatment would depend on the type of encephalitis the patient has developed.

Indexed as

COVID-19encephalitismeaslespreventiontreatment

Identifiers

PMID36412598
PMCPMC9680274
OpenAlexW4309613846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.