Evidence map›Paper›PMID 36412572›Full record

SynthesisInternational journal of immunopathology and pharmacology

Epidemiological and clinical characteristics of vaccinated COVID-19 patients: A meta-analysis and systematic review.

Wen Tian, Xingxiang Ren, Mei Han, Yuanyuan Zhang, Xu Gao, Zhihai Chen, Wei Zhang

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Wen TianCenter of Infectious Diseases, Beijing Ditan Hospital, 12638Capital Medical University, Beijing, China.
Xingxiang RenDepartment of Endocrinology, 594822Peking University International Hospital, Beijing, China.ORCID 0000-0002-5140-1256
Mei HanCentre for Evidence-Based Chinese Medicine, 47839Beijing University of Chinese Medicine, Beijing, China.
Yuanyuan ZhangBeijing Key Laboratory of Emerging Infectious Disease, Beijing Ditan Hospital, 12638Captital Medical University, Beijing, China.
Xu GaoCenter of Infectious Diseases, Beijing Ditan Hospital, 12638Capital Medical University, Beijing, China.
Zhihai ChenCenter of Infectious Diseases, Beijing Ditan Hospital, 12638Capital Medical University, Beijing, China.
Wei ZhangCenter of Infectious Diseases, Beijing Ditan Hospital, 12638Capital Medical University, Beijing, China.ORCID 0000-0001-7148-4776
Capital Medical University · CNBeijing Ditan Hospital · CNBeijing University of Chinese Medicine · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWith the global epidemic of coronavirus disease 2019 (COVID-19), vaccination rates are increasing globally. This study evaluated the relevant clinical manifestations of vaccinated COVID-19 patients.

methodsWe searched carefully in 11 databases such as PubMed, Embase, Scopus, Cochrane Library, Web of Science, Ovid, China National Knowledge Infrastructure Database, Wan Fang Data, Sinomed, VIP Database, and Reading Showing Database up to 26 March 2022. To search for articles that have described the characteristics of vaccinated patients including epidemiological and clinical symptoms. Statistical analysis of the extracted data using STATA 14.0.

resultsA total of 58 articles and 263,708 laboratory-confirmed COVID-19 patients were included. Most of the patients in the vaccinated group had more asymptomatic infection and fewer severe illnesses. There were significant differences in ethnicity, and strain infected with COVID-19, and comorbidities (hyperlipidemia, diabetes, obesity, kidney disease, immunocompromised, cardiovascular disease, and tumor) and symptoms (fever, cough, gastrointestinal symptoms, neurological symptoms, and dysgeusia/anosmia) between vaccinated group and unvaccinated group. Oxygen support, use of steroid, days in hospital, hospital treatment, ICU treatment, death, and poor prognosis were also significantly different.

conclusionCompared with the vaccinated group, patients in the unvaccinated group had a more severe clinical manifestations. Vaccines are also protective for infected people.

Indexed as

Cardiovascular DiseasesCOVID-19NeoplasmsChinaHumansResearch Designclinical characteristicsCOVID-19epidemiological characteristicsmeta-analysisvaccine

Identifiers

PMID36412572
PMCPMC9692180
OpenAlexW4309665249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.