Evidence map›Paper›PMID 36411876›Full record

ArticleJACC. Asia2022

Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization: CREDO-Kyoto PCI/CABG Registry.

Kyohei Yamaji, Hiroki Shiomi, Takeshi Morimoto, Yukiko Matsumura-Nakano, Natsuhiko Ehara, Hiroki Sakamoto, Yasuaki Takeji, Yusuke Yoshikawa, Ko Yamamoto, Eri T Kato and 46 more

Open access · goldAbstract read
In one paragraph

Article in JACC. Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

56 authors at 20 institutions in 1 country.

Kyohei YamajiDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Hiroki ShiomiDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takeshi MorimotoDepartment of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan.
Yukiko Matsumura-NakanoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Natsuhiko EharaDepartment of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Hiroki SakamotoDepartment of Cardiology, Shizuoka General Hospital, Shizuoka, Japan.
Yasuaki TakejiDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yusuke YoshikawaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ko YamamotoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Eri T KatoDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kazuaki ImadaDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Takeshi TadaDepartment of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan.
Ryoji TaniguchiDepartment of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan.
Ryusuke NishikawaDepartment of Cardiology, Shizuoka General Hospital, Shizuoka, Japan.
Tomohisa TadaDepartment of Cardiology, Shizuoka General Hospital, Shizuoka, Japan.
Takashi UegaitoDepartment of Cardiology, Kishiwada City Hospital, Kishiwada, Japan.
Tatsuya OgawaDepartment of Cardiovascular Surgery, Kishiwada City Hospital, Kishiwada, Japan.
Miho YamadaDepartment of Cardiology, Hamamatsu Rosai Hospital, Hamamatsu, Japan.
Teruki TakedaDepartment of Cardiology, Koto Memorial Hospital, Higashiomi, Japan.
Hiroshi EizawaDepartment of Cardiology, Kobe City Nishi-Kobe Medical Center, Kobe, Japan.
Nobushige TamuraDepartment of Cardiovascular Surgery, Kindai University Nara Hospital, Ikoma, Japan.
Keiichi TambaraDepartment of Cardiovascular Surgery, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Satoru SuwaDepartment of Cardiology, Juntendo University Shizuoka Hospital, Izunokuni, Japan.
Manabu ShirotaniDepartment of Cardiology, Kindai University Nara Hospital, Ikoma, Japan.
Toshihiro TamuraDepartment of Cardiology, Tenri Hospital, Tenri, Japan.
Moriaki InokoDepartment of Cardiology, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
Junichiro NishizawaDepartment of Cardiovascular Surgery, Hamamatsu Rosai Hospital, Hamamatsu, Japan.
Masahiro NatsuakiDepartment of Cardiovascular Medicine, Saga University, Saga, Japan.
Hiroshi SakaiDepartment of Cardiology, Shiga University of Medical Science Hospital, Otsu, Japan.
Takashi YamamotoDepartment of Cardiology, Shiga University of Medical Science Hospital, Otsu, Japan.
Naoki KanemitsuDepartment of Cardiovascular Surgery, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan.
Nobuhisa OhnoDepartment of Cardiovascular Surgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan.
Katsuhisa IshiiDepartment of Cardiology, Kansai Denryoku Hospital, Osaka, Japan.
Akira MaruiDepartment of Cardiovascular Surgery, Kokura Memorial Hospital, Kitakyushu, Japan.
Hiroshi TsuneyoshiDepartment of Cardiovascular Surgery, Shizuoka General Hospital, Shizuoka, Japan.
Yasuhiko TeraiDepartment of Cardiovascular Surgery, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.
Shogo NakayamaDepartment of Cardiovascular Surgery, Osaka Red Cross Hospital, Osaka, Japan.
Kazuhiro YamazakiDepartment of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Mamoru TakahashiDepartment of Cardiology, Shimabara Hospital, Kyoto, Japan.
Takashi TamuraDepartment of Cardiology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan.
Jiro EsakiDepartment of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, Kyoto, Japan.
Shinji MikiDepartment of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Japan.
Tomoya OnoderaDepartment of Cardiology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.
Hiroshi MabuchiDepartment of Cardiology, Koto Memorial Hospital, Higashiomi, Japan.
Yutaka FurukawaDepartment of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Masaru TanakaDepartment of Cardiology, Osaka Red Cross Hospital, Osaka, Japan.
Tatsuhiko KomiyaDepartment of Cardiovascular Surgery, Kurashiki Central Hospital, Kurashiki, Japan.
Yoshiharu SogaDepartment of Cardiovascular Surgery, Kokura Memorial Hospital, Kitakyushu, Japan.
Michiya HanyuDepartment of Cardiovascular Surgery, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan.
Takenori DomeiDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Kenji AndoDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Kazushige KadotaDepartment of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan.
Kenji MinatoyaDepartment of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yoshihisa NakagawaDepartment of Cardiology, Shiga University of Medical Science Hospital, Otsu, Japan.
Takeshi KimuraDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
CREDO-Kyoto PCI/CABG Registry Investigators
Kyoto University · JPKokura Memorial Hospital · JPKurashiki Central Hospital · JPShizuoka General Hospital · JPKishiwada City Hospital · JPKitano Hospital · JPKobe City Medical Center General Hospital · JPKobe City Nishi-Kobe Medical Center · JPHamamatsu Rosai Hospital · JPHyogo Prefectural Amagasaki General Medical Center · JPJapanese Red Cross Society Wakayama Medical Center · JPJuntendo University Shizuoka Hospital · JPKindai University · JPMitsubishi Kyoto Hospital · JPOsaka Red Cross Hospital · JPShizuoka City Hospital · JPKoto Hospital · JPSakakibara Hospital · JPShiga University of Medical Science Hospital · JPHyogo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes is a well-known risk factor for adverse outcomes after coronary revascularization. Objectives: This study sought to determine high-risk subgroups in whom the excess risks of diabetes relative to nondiabetes are particularly prominent and thus may benefit from more aggressive interventions. Methods: The study population consisted of 39,427 patients (diabetes: n = 15,561; nondiabetes: n = 23,866) who underwent first percutaneous coronary intervention (n = 33,144) or coronary artery bypass graft (n = 6,283) in the pooled CREDO-Kyoto PCI/CABG (Coronary Revascularization Demonstrating Outcome Study in Kyoto Percutaneous Coronary Intervention/Coronary Artery Bypass Graft) registry. The primary outcome measure was major adverse cardiovascular and cerebral endpoints (MACCE), which was defined as a composite of all-cause death, myocardial infarction, and stroke. Results: With median follow-up of 5.6 years, diabetes was associated with significantly higher adjusted risks for MACCE. The excess adjusted risks of diabetes relative to nondiabetes for MACCE increased with younger age (≤64 years: adjusted HR: 1.30; 95% CI: 1.19-1.41; Conclusions: The excess risk of diabetes relative to nondiabetes for MACCE was profound in the younger population. This observation suggests more aggressive interventions for secondary prevention in patients with diabetes might be particularly relevant in younger patients.

Indexed as

AMI, acute myocardial infarctionCABG, coronary artery bypass graftcoronary artery bypass graftdiabetesMACCE, major adverse cardiovascular and cerebral endpointsMI, myocardial infarctionPCI, percutaneous coronary interventionpercutaneous coronary interventionRCT, randomized controlled trialTVR, target vessel revascularization

Identifiers

PMID36411876
PMCPMC9675601
OpenAlexW4223495402

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.