Evidence map›Paper›PMID 36411827›Full record

ArticleJournal of multidisciplinary healthcare2022

Knowledge of Drug-Food Interactions Among Healthcare Professionals Working in Public Hospitals in Ethiopia.

Natanim Degefu, Melaku Getachew, Firehiwot Amare

Open access · goldAbstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Observational
  2. Article
  3. KG-DFI: A Prediction of Drug-Food Interactions Based on Knowledge Graph Embedding.Computational and structural biotechnology journal · 2026
    Article
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  6. Observational
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  8. South African Dietitians' Knowledge and Perceptions of Food-Drug Interactions and Factors Affecting It.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Natanim DegefuDepartment of Pharmaceutics, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.ORCID 0000-0001-8727-8950
Melaku GetachewDepartment of Emergency Medicine and Critical Care, School of Medicine, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.ORCID 0000-0002-1816-2484
Firehiwot AmareDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-9218-4008
Haramaya University · ETAddis Ababa University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Drug-food interactions can result in unfavorable outcomes during the treatment of patients. Healthcare professionals (HCPs) should advise patients on drug-food interactions. Knowledge of such interactions is crucial to avoid their occurrence. However, there is no information regarding the knowledge of HCPs about drug-food interactions in Harari Regional State. Objective: To assess knowledge of drug-food interactions and associated factors among HCPs working in public hospitals in Harari Regional State, Eastern Ethiopia from April 15 to May 15, 2022. Methods: A cross-sectional study was conducted in public hospitals in Harari Regional State, Eastern Ethiopia, among 251 HCPs. After stratification was done based on profession (pharmacists, nurses, and doctors), the sample size was proportionally allocated for the respective groups. Data were collected using a standardized self-administered questionnaire, entered into Epi-Data 3.1 and analyzed using Statistical Package for Social Sciences 26.0. Descriptive statistics were used to summarize variables. Multivariable logistic regression was done to determine factors associated with knowledge of drug-food interactions. P < 0.05 was used to declare significant association. Results: Among the HCPs who completed the questionnaire, 56 (22.3%), 36 (14.3%), and 159 (63.3%) were doctors, pharmacists, and nurses, respectively. The majority of the HCPs were males (174 (69.3%)). The mean age of the HCPs was 27.6±3.8. The mean knowledge score±SD of the HCPs was 28.6±6.6 out of an overall score of 59. The HCPs poorly identified drug-food interactions and the correct administration time of drugs relative to meals. Being a pharmacist (AOR: 2.8, CI: 1.3-6.4, p-value=0.012), and working at a tertiary hospital (AOR: 3.9, CI: 2.1-7.3, p-value <0.001), were associated with higher knowledge of drug-food interactions. Conclusion: The HCPs in this study had inadequate knowledge of drug-food interactions. Thus, additional educational courses and training should be provided in order to improve knowledge regarding drug-food interaction.

Indexed as

drug–food interactionhealthcare professionalsknowledgepublic hospitals

Identifiers

PMID36411827
PMCPMC9675322
OpenAlexW4309019374

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.