Evidence map›Paper›PMID 36411798›Full record

ArticlemicroPublication biology2022

Inhibition of the Exocyst Complex with Endosidin 2 Reduces Polarized Growth in

Eric Bormann, Rholee Xu, Clare Nargi, Min Wu, Luis Vidali

Open access · greenAbstract read
In one paragraph

Article in microPublication biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eric BormannDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, USA.
Rholee XuBioinformatics and Computational Biology Program, Worcester Polytechnic Institute, Worcester, MA, USA.
Clare NargiDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, USA.
Min WuDepartment of Mathematical Sciences, Worcester Polytechnic Institute, Worcester, MA, USA.
Luis VidaliDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, USA.
Worcester Polytechnic Institute · US

Funding

Composition, in vivo dynamics, and regulation of the exocyst in plant cellsR15GM134493 · NIGMS · WORCESTER POLYTECHNIC INSTITUTE · PI VIDALI, LUIS · 2019 to 2019
$448k
NIGMS NIH HHS R15 GM134493
6 · The paper itself

Abstract

Endosidin 2 (ES2) is a cell-permeable drug that binds to the Exo70 subunit of the exocyst complex, disrupting the final stages of exocytosis. This allows for a dose-dependent control over the process of exocytosis and greater ease in studying exocytic-dependent processes such as polarized cell growth. ES2 was utilized in studying polarized cell growth in the moss

Identifiers

PMID36411798
PMCPMC9674970
OpenAlexW4309663441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.