Evidence map›Paper›PMID 36411696›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2022

Application of mesenchymal stem cells in tumor therapy.

Xiangling Tang, Yu Zhang, Xionghao Liu, Mujun Liu

Abstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiangling TangGenetics Laboratory, College of Life Science, Central South University, Changsha 410078. tangxiangling@sklmg.edu.cn.
Yu ZhangGenetics Laboratory, College of Life Science, Central South University, Changsha 410078.
Xionghao LiuHunan Key Laboratory of Medical Genetics, Changsha 410078.
Mujun LiuHunan Key Laboratory of Basic and Applied Hematology, Changsha 410008, China. liumujun03@csu.ed.cn.

Funding

the Graduate Education and Teaching Reform Research Project of Central South University 2020JGB105the Natural Science Foundation of Hunan Province 2021JJ30801
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are multipotent stem cells that exist widely in the human body, which can self-renewal and differentiate into different types of cell. Due to its advantages of tumor tissue tropism and easy to be engineered, it has been widely used in cancer treatment research recently. However, the tumor-promoting or anti-tumor effect of MSCs is controversial, especially for unmodified MSCs. Therefore, researchers are more inclined to use MSCs as carriers to engineer them. With the deepening in understanding of vesicles, it is found that the vesicles derived from MSCs seem to have greater advantages as carriers. Although the current research of MSCs in the treatment of tumors has been initiated in the clinic, there are still many problems to be solved in the pre-clinical application.

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationHumanscombination therapyextracellular vesiclesgenetic modificationmesenchymal stem cellstumor treatment

Identifiers

PMID36411696
PMCPMC10930360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.