Evidence map›Paper›PMID 36411624›Full record

ArticleBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2022

[

Naresh Damuka, Nagaraju Bashetti, Akiva Mintz, Avinash H Bansode, Mack Miller, Ivan Krizan, Cristina Furdui, Bhuvanachandra Bhoopal, Krishna Kumar Gollapelli, J V Shanmukha Kumar and 4 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
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  5. Review
  6. Exploring microtubule dynamics in Alzheimer's disease: Longitudinal assessment using [Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Naresh DamukaDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Nagaraju BashettiDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Andhra Pradesh, India.
Akiva MintzDepartment of Radiology, Columbia University, New York, NY, United States.
Avinash H BansodeDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Mack MillerDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Ivan KrizanDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Cristina FurduiDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Bhuvanachandra BhoopalDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Krishna Kumar GollapelliDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, United States.
J V Shanmukha KumarDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Andhra Pradesh, India.
Gagan DeepDepartment of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Greg DuganDepartment of Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Mark ClineDepartment of Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Kiran Kumar Solingapuram SaiDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, United States. Electronic address: ksolinga@wakehealth.edu.
Wake Forest University · USColumbia University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
NCATS NIH HHS UL1 TR001420NCI NIH HHS P30 CA012197
6 · The paper itself

Abstract

Over production of reactive oxygen species (ROS) caused by altered redox regulation of signaling pathways is common in many types of cancers. While PET imaging is recognized as the standard tool for cancer imaging, there are no clinically-approved PET radiotracers for ROS-imaging in cancer diagnosis and treatment. An ascorbate-based radio ligand promises to meet this urgent need. Our laboratory recently synthesized [

Indexed as

Head and Neck NeoplasmsLiver NeoplasmsAnimalsAscorbic AcidDoxorubicinLigandsMaleMicePrimatesRatsReactive Oxygen SpeciesRodentiaSquamous Cell Carcinoma of Head and NeckTissue DistributionAscorbic AcidDoxorubicinLigandsReactive Oxygen SpeciesAscorbateBiodistribution, RadioligandsCancerPositron emission tomography imagingReactive oxygen species

Identifiers

PMID36411624
PMCPMC11017304
OpenAlexW4307573937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.