Evidence map›Paper›PMID 36411555›Full record

ReviewCurrent molecular medicine2024

EBV-microRNAs as Potential Biomarkers in EBV-related Fever: A Narrative Review.

Wei-Ting Wang, Yun Yang, Yang Zhang, Yi-Ning Le, Yu-Lin Wu, Yi-Yi Liu, Yan-Jie Tu

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wei-Ting WangSchool of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai (201203), China.
Yun YangSchool of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai (201203), China.ORCID 0000-0001-9429-8204
Yang ZhangInformation Center of Science and Technology, Shanghai Innovation Center of TCM Health Service, Shanghai University of Traditional Chinese Medicine, Shanghai (201203), China.
Yi-Ning LeNational Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai (200433), China.
Yu-Lin WuSchool of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai (201203), China.
Yi-Yi LiuLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai (200032), China.
Yan-Jie TuDepartment of Febrile Disease, Basic Medical College, Shanghai University of Traditional Chinese Medicine, Shanghai (201203), China.ORCID 0000-0002-9502-1730
Shanghai University of Traditional Chinese Medicine · CNSecond Military Medical University · CNShanghai Innovative Research Center of Traditional Chinese Medicine · CN

Funding

Climbing and Trekking Talent Training Program in Basic Medical College, Shanghai University of Traditional Chinese Medicine A1-GY20-101-0101Ministry of Science and Technology of China 2018YFC1704102National Natural Science Foundation of China 81904072Training Program of Xing-lin Heritage-type Talents in Shanghai University of Traditional Chinese Medicine A1-W20-205-01-0402-18
6 · The paper itself

Abstract

At present, timely and accurate diagnosis and effective treatment of Epstein- Barr Virus (EBV) infection-associated fever remain a difficult challenge. EBV encodes 44 mature microRNAs (miRNAs) that inhibit viral lysis, adjust inflammatory response, regulate cellular apoptosis, promote tumor genesis and metastasis, and regulate tumor cell metabolism. Herein, we have collected the specific expression data of EBV-miRNAs in EBV-related fevers, including infectious mononucleosis (IM), EBVassociated hemophagocytic lymphohistiocytosis (EBV-HLH), chronic active EBV infection (CAEBV), and EBV-related tumors, and proposed the potential value of EBVmiRNAs as biomarkers to assist in the identification, diagnosis, and prognosis of EBVrelated fever, as well as therapeutic targets for drug development.

Indexed as

Epstein-Barr Virus InfectionsInfectious MononucleosisMicroRNAsBiomarkersHerpesvirus 4, HumanHumansBiomarkersMicroRNAsbiomarker.EBV-related feversEpstein-BarrmicroRNAstherapeutic targetsvirus

Identifiers

PMID36411555
PMCPMC10825793
OpenAlexW4309666800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.