Trial reportBMC public health2022
MomsTalkShots, tailored educational app, improves vaccine attitudes: a randomized controlled trial.
Trial report in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02898688 (A Comprehensive Pre-Natal Intervention to Increase Vaccine Coverage), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Comprehensive Pre-Natal Intervention to Increase Vaccine Coverage (P3+): Practice, Provider, Patient Level Interventions
Who cites it
12 citing papers in PubMed.
- Human-centred design bolsters vaccine confidence in the Philippines: results of a randomised controlled trial.BMJ global health · 2023Trial
- Digital vaccines for immunization equity: an approach to strengthen vaccine delivery and public trust in low- and middle-income countries.JAMIA open · 2026Review
- Utilization of Provider-Patient Communication Tools and Approaches to Facilitate Vaccine Confidence: A Systematic Review.Vaccines · 2025Review
- Immunity Awareness-Strategies to Improve the Degree of Acceptance of Vaccines: A Systematic Review.Vaccines · 2025Review
- Systematic review and meta-analysis of interventions to increase the uptake of vaccines recommended during pregnancy.NPJ vaccines · 2025Article
- [Digital innovations in vaccination communication].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Article
- COVID-19 and influenza vaccine Hesitancy among adults hospitalized in the United States, 2019-2022.Vaccine · 2025Article
- Review
- The Obstetrician's Role in Pregnant Women's Decision-Making Process Regarding Influenza and COVID-19 Vaccination.Vaccines · 2023Article
- Influenza vaccination landscape in Italy: A comprehensive study through the OBVIOUS project lens.Human vaccines & immunotherapeutics · 2023Article
- Article
- Barriers and Facilitators Influencing Parents' Willingness to Follow Healthcare Provider Guidance for Addressing Behaviors Linked to Early Childhood Obesity Risk: A Qualitative Descriptive Study.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & PractitionersArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
backgroundMany pregnant women and parents have concerns about vaccines. This analysis examined the impact of MomsTalkShots, an individually tailored educational application, on vaccine attitudes of pregnant women and mothers.
methodsMomsTalkShots was the patient-level component of a multi-level intervention to improve maternal and infant vaccine uptake that also included provider- and practice-level interventions. The impact of these interventions was studied using a two-by-two factorial design, randomizing at both the patient- and the practice-level. Study staff recruited pregnant women from a diverse set of prenatal care practices in Colorado and Georgia between June 2017 and July 2018. All participants (n = 2087) received a baseline survey of maternal and infant vaccine intentions and attitudes, and two follow-up surveys at least 1 month and 1 year after their infant's birth, respectively. Half of participants (n = 1041) were randomly assigned to receive educational videos through MomsTalkShots, algorithmically tailored to their vaccine intentions, attitudes, and demographics. Since the practice/provider intervention did not appear impactful, this analysis focused on MomsTalkShots regardless of the practice/provider intervention.
resultsBy 1 month post-birth, MomsTalkShots increased perceived risk of maternal influenza disease (61% among MomsTalkShots recipients vs 55% among controls; Odds Ratio: 1.61, 95% Confidence Interval: 1.23-2.09), confidence in influenza vaccine efficacy (73% vs 63%; OR: 1.97, 95%CI: 1.47-2.65), and perceived vaccine knowledge (55% vs 48%; OR: 1.39, 95%CI: 1.13-1.72). Among those intending not to vaccinate at baseline, MomsTalkShots increased perceived risk of maternal influenza disease (38% vs 32%; OR: 2.07, 95%CI: 1.15-3.71) and confidence in influenza vaccine efficacy (44% vs 28%; OR: 2.62, 95%CI: 1.46-4.69). By 1 year post-birth, MomsTalkShots increased perceived vaccine knowledge (62% vs 50%; OR: 1.74, 95%CI: 1.36-2.24) and trust in vaccine information from obstetricians and pediatricians (64% vs 55%; OR: 1.53, 95%CI: 1.17-2.00). Among those uncertain about vaccinating at baseline, MomsTalkShots increased perceived vaccine knowledge (47% vs 12%; OR: 6.89, 95%CI: 1.52-31.25) and reduced infant vaccine safety concerns (71% vs 91%; OR: 0.24, 95%CI: 0.06-0.98).
conclusionsMomsTalkShots improved pregnant women's and mothers' knowledge and perceptions of maternal and infant vaccines and the diseases they prevent, and offers a scalable tool to address vaccine hesitancy.
trial registrationRegistered at Clinicaltrials.gov on 13/09/2016 (registration number: NCT02898688).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.