Evidence map›Paper›PMID 36411394›Full record

ReviewNeuroscience bulletin2023

Depression and Anxiety During the COVID-19 Pandemic: Epidemiology, Mechanism, and Treatment.

Chunyan Zhu, Ting Zhang, Qianqian Li, Xingui Chen, Kai Wang

Open access · hybridAbstract readReview
In one paragraph

Review in Neuroscience bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
22.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 126 citations in OpenAlex.

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  20. [Gender differences in acylcarnitine metabolism among patients with depression disorder].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chunyan Zhu *School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230032, China.
Ting Zhang *Department of Psychiatry, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Qianqian LiDepartment of Psychiatry, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Xingui ChenDepartment of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Kai WangSchool of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230032, China. wangkai1964@126.com.
Anhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Coronavirus Disease 2019 (COVID-19) pandemic has had an adverse impact on the physical and mental health of the public worldwide. In addition to illness in patients with COVID-19, isolated people and the general population have experienced mental health problems due to social distancing policies, mandatory lockdown, and other psychosocial factors, and the prevalence of depression and anxiety significantly increased during the pandemic. The purpose of this review is to elucidate the epidemiology, contributing factors, and pathogenesis of depression and anxiety. during the pandemic. These findings indicate that physicians and psychiatrists should pay more attention to and identify those with a high risk for mental problems, such as females, younger people, unmarried people, and those with a low educational level. In addition, researchers should focus on identifying the neural and neuroimmune mechanisms involved in depression and anxiety, and assess the intestinal microbiome to identify effective biomarkers. We also provide an overview of various intervention methods, including pharmacological treatment, psychological therapy, and physiotherapy, to provide a reference for different populations to guide the development of optimized intervention methods.

Indexed as

AnxietyCOVID-19DepressionPandemicsAge FactorsCommunicable Disease ControlComorbidityHumansSex FactorsSocioeconomic FactorsAnxietyCOVID-19DepressionEpidemiologyInterventionMechanism

Identifiers

PMID36411394
PMCPMC9685018
OpenAlexW4309667754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.