Evidence map›Paper›PMID 36411317›Full record

ArticleScientific reports2022

Assessing spermatozoal small ribonucleic acids and their relationship to blastocyst development in idiopathic infertile males.

Matthew Hamilton, Stewart Russell, Karen Menezes, Sergey I Moskovtsev, Clifford Librach

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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  13. Identification of protein candidates in spermatozoa of water buffalo (Frontiers in cell and developmental biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matthew HamiltonCReATe Fertility Centre, Toronto, ON, Canada.
Stewart RussellCReATe Fertility Centre, Toronto, ON, Canada. stewart@createivf.com.
Karen MenezesCReATe Fertility Centre, Toronto, ON, Canada.
Sergey I MoskovtsevCReATe Fertility Centre, Toronto, ON, Canada.
Clifford LibrachCReATe Fertility Centre, Toronto, ON, Canada.
CReATe Fertility Centre · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical testing strategies for diagnosing male factor infertility are limited. A deeper analysis of spermatozoa-derived factors could potentially diagnose some cases of 'unexplained infertility'. Spermatozoa carry a rich and dynamic profile of small RNAs, which have demonstrated potential developmental importance and association with fertility status. We used next-generation sequencing to correlate sperm small RNA profiles of normozoospermic males (n = 54) with differing blastocyst development rates, when using young donor oocytes. While ribosomal RNAs accounted for the highest number of sequencing reads, transfer RNA fragments of tRNA

Indexed as

Infertility, MaleMicroRNAsBlastocystHumansMaleRNA, TransferSemenMicroRNAsRNA, Transfer

Identifiers

PMID36411317
PMCPMC9678953
OpenAlexW4309534020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.