Evidence map›Paper›PMID 36411304›Full record

ArticleScientific reports2022

The association between expressive language skills and adaptive behavior in individuals with Down syndrome.

Laura Del Hoyo Soriano, Jennifer Catalina Villarreal, Audra Sterling, Jamie Edgin, Elizabeth Berry-Kravis, Debra R Hamilton, Angela John Thurman, Leonard Abbeduto

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Language and Ageing in Adults With Down Syndrome: An Analysis of Receptive and Expressive Language Measures.Journal of applied research in intellectual disabilities : JARID · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Laura Del Hoyo SorianoMIND Institute, University of California Davis, 2825 50Th Street, Sacramento, CA, USA. ldelhoyo@ucdavis.edu.
Jennifer Catalina VillarrealMIND Institute, University of California Davis, 2825 50Th Street, Sacramento, CA, USA.
Audra SterlingWaisman Center and Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, WI, USA.
Jamie EdginDepartment of Psychology, University of Arizona, Tucson, AZ, USA.
Elizabeth Berry-KravisDepartments of Pediatrics, Neurological Sciences and Biochemistry, Rush University Medical Center, Chicago, IL, USA.
Debra R HamiltonDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Angela John ThurmanMIND Institute, University of California Davis, 2825 50Th Street, Sacramento, CA, USA.
Leonard AbbedutoMIND Institute, University of California Davis, 2825 50Th Street, Sacramento, CA, USA.
University of California, Davis · USEmory University · USRush University Medical Center · USUniversity of Arizona · USUniversity of Wisconsin–Madison · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Expressive Language Sampling as an Outcome MeasureR01HD074346 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ABBEDUTO, LEONARD J. · 2013 to 2017
$3.9M
NCATS NIH HHS UL1 TR001860NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD074346
6 · The paper itself

Abstract

The primary goal of this study was to determine whether expressive language skills contribute to adaptive behavior (e.g., socialization and daily living skills) in children, adolescents, and young adults with Down syndrome (DS) whilst controlling for age and nonverbal cognitive ability. Expressive language was assessed using the psychometrically validated Expressive Language Sampling (ELS) conversation and narration procedures. The language produced was transcribed and analyzed to yield measures of expressive vocabulary, syntax, and intelligibility. Socialization and daily living skills of participants with DS were measured with the Vineland Adaptive Behavior Scales, 2nd edition (VABS-2) parent/caregiver rating form. Our results show that the three ELS measures were significantly correlated with multiple measures from the VABS-2 when controlling for age. Several correlations remained significant even when nonverbal cognitive ability was included as a control variable. Our results suggest that expressive language skills contribute to adaptive behavior in children, adolescents, and young adults with DS regardless of age and some of these associations are not explained solely by overall cognitive delays. Further studies including longitudinal data are needed to extend our results.

Indexed as

Down SyndromeAdaptation, PsychologicalAdolescentChildCognitionHumansLanguageSocializationYoung Adult

Identifiers

PMID36411304
PMCPMC9678860
OpenAlexW4309661698

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.