Evidence map›Paper›PMID 36411201›Full record

ReviewTrends in microbiology2023

Bacterial chemotaxis in human diseases.

Bibi Zhou, Christine M Szymanski, Arden Baylink

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. ZnbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Collective bacterial condensation is fundamentally constrained by the emergence of active turbulence.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Structure and signaling mechanism ofbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Microorganisms · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Functional analysis of cyclic diguanylate-modulating proteins inbioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bibi ZhouUniversity of Georgia, Department of Microbiology and Complex Carbohydrate Research Center, Athens, GA 30602, USA.
Christine M SzymanskiUniversity of Georgia, Department of Microbiology and Complex Carbohydrate Research Center, Athens, GA 30602, USA.
Arden BaylinkWashington State University, Department of Veterinary Microbiology and Pathology, Pullman, WA 99164, USA. Electronic address: arden.baylink@wsu.edu.

Funding

Understanding the molecular mechanisms and biological functions of a novel bleach-sensing bacterial receptor in shaping host-associated bacterial populations in response to host inflammationR00AI148587 · NIAID · WASHINGTON STATE UNIVERSITY · PI BAYLINK, ARDEN · 2022 to 2023
$498k
Understanding the molecular mechanisms and biological functions of a novel bleach-sensing bacterial receptor in shaping host-associated bacterial populations in response to host inflammationK99AI148587 · NIAID · UNIVERSITY OF OREGON · PI BAYLINK, ARDEN · 2020 to 2021
$235k
NIAID NIH HHS K99 AI148587NIAID NIH HHS R00 AI148587
6 · The paper itself

Abstract

To infect and cause disease, bacterial pathogens must localize to specific regions of the host where they possess the metabolic and defensive acumen for survival. Motile flagellated pathogens exercise control over their localization through chemotaxis to direct motility based on the landscape of exogenous nutrients, toxins, and molecular cues sensed within the host. Here, we review advances in understanding the roles chemotaxis plays in human diseases. Chemotaxis drives pathogen colonization to sites of inflammation and injury and mediates fitness advantages through accessing host-derived nutrients from damaged tissue. Injury tropism may worsen clinical outcomes through instigating chronic inflammation and subsequent cancer development. Inhibiting bacterial chemotactic systems could act synergistically with antibacterial medicines for more effective and specific eradication.

Indexed as

BacteriaChemotaxisBacterial ProteinsHumansInflammationBacterial Proteinsbacterial pathogenesischemotaxischronic inflammationmotility

Identifiers

PMID36411201
PMCPMC11238666

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.