Evidence map›Paper›PMID 36409939›Full record

ArticleThe western journal of emergency medicine2022

Implementation of a Leave-behind Naloxone Program in San Francisco: A One-year Experience.

Kathy T LeSaint, Juan Carlos C Montoy, Eric C Silverman, Maria C Raven, Samuel L Schow, Phillip O Coffin, John F Brown, Mary P Mercer

Abstract read
In one paragraph

Article in The western journal of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Assessment of a County-Wide, Pan-First Responder Take-Home Naloxone Program in Denver, Colorado.Journal of the American College of Emergency Physicians open · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Epidemiology of 911 Calls for Opioid Overdose in Nogales, Arizona.The western journal of emergency medicine · 2025
    Article
  7. Implementation of an EMS-based naloxone distribution program: A qualitative evaluation.Journal of the American College of Emergency Physicians open · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathy T LeSaintUniversity of California, San Francisco, Department of Emergency Medicine, San Francisco, California.
Juan Carlos C MontoyUniversity of California, San Francisco, Department of Emergency Medicine, San Francisco, California.
Eric C SilvermanUniversity of California, San Francisco, Department of Emergency Medicine, San Francisco, California.
Maria C RavenUniversity of California, San Francisco, Department of Emergency Medicine, San Francisco, California.
Samuel L SchowSan Francisco Fire Department, San Francisco, California.
Phillip O CoffinUniversity of California, San Francisco, Department of Emergency Medicine, San Francisco, California.
John F BrownSan Francisco Department of Public Health, San Francisco, California.
Mary P MercerUniversity of California, San Francisco, Department of Emergency Medicine, San Francisco, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn response to the ongoing opioid overdose crisis, US officials urged the expansion of access to naloxone for opioid overdose reversal. Since then, emergency medical services' (EMS) dispensing of naloxone kits has become an emerging harm reduction strategy.

methodsWe created a naloxone training and low-barrier distribution program in San Francisco: Project FRIEND (First Responder Increased Education and Naloxone Distribution). The team assembled an advisory committee of stakeholders and subject-matter experts, worked with local and state EMS agencies to augment existing protocols, created training curricula, and developed a naloxone-distribution data collection system. Naloxone kits were labeled for registration and data tracking. Emergency medical technicians and paramedics were asked to distribute naloxone kits to any individuals (patient or bystander) they deemed at risk of experiencing or witnessing an opioid overdose, and to voluntarily register those kits.

resultsTraining modalities included a video module (distributed to over 700 EMS personnel) and voluntary, in-person training sessions, attended by 224 EMS personnel. From September 25, 2019-September 24, 2020, 1,200 naloxone kits were distributed to EMS companies. Of these, 232 kits (19%) were registered by EMS personnel. Among registered kits, 146 (63%) were distributed during encounters for suspected overdose, and 103 (44%) were distributed to patients themselves. Most patients were male (n = 153, 66%) and of White race (n = 124, 53%); median age was 37.5 years (interquartile range 31-47).

conclusionWe describe a successful implementation and highlight the feasibility of a low-threshold, leave-behind naloxone program. Collaboration with multiple entities was a key component of the program's success.

Indexed as

Drug OverdoseOpiate OverdoseAdultFemaleHumansMaleNaloxoneNarcotic AntagonistsSan FranciscoNaloxoneNarcotic Antagonists

Identifiers

PMID36409939
PMCPMC9683755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.