Evidence map›Paper›PMID 36409915›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Longitudinal in vivo Ca

Liang Li, Xue Feng, Fang Fang, David A Miller, Shaobo Zhang, Pei Zhuang, Haoliang Huang, Pingting Liu, Junting Liu, Nripun Sredar and 6 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Variant-to-gene mapping identifiesbioRxiv : the preprint server for biology · 2026
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Liang LiSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.ORCID 0000-0002-6292-5995
Xue FengSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.ORCID 0000-0002-9624-9665
Fang FangSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.
David A MillerDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208.ORCID 0000-0002-1630-1233
Shaobo ZhangDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94143.
Pei ZhuangSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.
Haoliang HuangSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.
Pingting LiuSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.ORCID 0000-0003-1601-2818
Junting LiuSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.ORCID 0000-0002-2099-0190
Nripun SredarSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.
Liang LiuSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.ORCID 0000-0003-4712-7626
Yang SunSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.
Xin DuanDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94143.
Jeffrey L GoldbergSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208.ORCID 0000-0001-5089-1196
Yang HuSpencer Center for Vision Research, Department of Ophthalmology, Byers Eye Institute at Stanford University School of Medicine, Palo Alto, CA 94304.ORCID 0000-0002-7980-1649

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Retinal Ganglion Cell Replacement in Optic NeuropathiesU24EY029903 · NEI · STANFORD UNIVERSITY · PI CALKINS, DAVID J., GOLDBERG, JEFFREY L · 2018 to 2024
$7.5M
Elucidating Neuron-Intrinsic Molecular Mechanisms of Optic Nerve RegenerationR01EY024932 · NEI · TEMPLE UNIV OF THE COMMONWEALTH · PI Yang Hu · 2015 to 2026
$4.8M
Neuroprotection by Modulating ER Stress in GlaucomaR01EY023295 · NEI · TEMPLE UNIV OF THE COMMONWEALTH · PI HU, YANG · 2013 to 2022
$3.8M
The role of primary cilia in glaucoma pathogenesisR01EY025295 · NEI · STANFORD UNIVERSITY · PI Yang Sun · 2016 to 2026
$3.5M
Mechanisms Underlying Type II Cadherin Guided Assembly of Retinal CircuitsR01EY030138 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Xin Duan · 2020 to 2026
$3.2M
Clinical glaucoma management enabled by visible-light OCTU01EY033001 · NEI · NORTHWESTERN UNIVERSITY · PI SCHUMAN, JOEL S, ZHANG, HAO F · 2021 to 2025
$3.2M
Optineurin dysfunction induces neurodegeneration in normal tension glaucoma by a novel molecular mechanismR01EY032518 · NEI · STANFORD UNIVERSITY · PI Yang Hu · 2022 to 2026
$2.7M
Investigating oxygen metabolism in diabetic retinopathyR01EY026078 · NEI · NORTHWESTERN UNIVERSITY · PI SHEIBANI, NADER, ZHANG, HAO F · 2016 to 2020
$2.3M
Gene Expression Regulatory Pathways and Retinal Ganglion Cell NeuroprotectionR01EY032416 · NEI · STANFORD UNIVERSITY · PI GOLDBERG, JEFFREY L, KAPILOFF, MICHAEL SETH · 2021 to 2024
$2.2M
Investigating nanoscale neuronal damages in early glaucoma towards clinical optical detectionR01EY029121 · NEI · NORTHWESTERN UNIVERSITY · PI LIU, XIAORONG, ZHANG, HAO F · 2018 to 2021
$2.0M
Developing Novel Neuroprotective Strategies for EAE/Optic NeuritisR01EY028106 · NEI · STANFORD UNIVERSITY · PI HU, YANG · 2018 to 2021
$1.9M
NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY023295NEI NIH HHS R01 EY024932NEI NIH HHS R01 EY025295NEI NIH HHS R01 EY026078NEI NIH HHS R01 EY028106NEI NIH HHS R01 EY028287NEI NIH HHS R01 EY029121NEI NIH HHS R01 EY030138NEI NIH HHS R01 EY032159NEI NIH HHS R01 EY032416NEI NIH HHS R01 EY032518NEI NIH HHS U01 EY033001NEI NIH HHS U24 EY029903
6 · The paper itself

Abstract

Retinal ganglion cells (RGCs) are heterogeneous projection neurons that convey distinct visual features from the retina to brain. Here, we present a high-throughput in vivo RGC activity assay in response to light stimulation using noninvasive Ca

Indexed as

GlaucomaRetinal Ganglion CellsAnimalsBrainDiagnostic ImagingMiceRetinaCa2+ imagingglaucomain vivoretinal ganglion cellsingle cell

Identifiers

PMID36409915
PMCPMC9889883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.