ArticlePloS one2022
Prevalence, causes, impacts, and management of needle phobia: An international survey of a general adult population.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Qualitative Exploration Study of Healthcare Professionals' Perspectives in Haemodialysis Needling to Enhance Patients' Overall Experience
Assessment of Maxillary Local Anesthesia Infiltration Efficiency and Adult Patient Satisfaction: Needle-free Jet vs Conventional Syringe in Simple Tooth Extraction in a Single-blinded, Randomized Controlled Trial
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Analyzing the impact of subcutaneous injection needle, device, and administration characteristics on patient pain, anxiety, and safety: a systematic literature review.Drug delivery · 2026Pooled it
- Reducing distress during vaccine injections: 2026 clinical practice guideline update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Guideline
- A Systematic Review and Meta-Analysis of Psychological Interventions for Reducing Distress During Vaccine Injections.The Clinical journal of pain · 2026Pooled it
- Rapid local anesthesia in children enhanced by STAR particles: a first-in-humans, randomized clinical trial.Drug delivery and translational research · 2026Trial
- LR3-LI4 needling side and configuration are associated with phase-specific cortical activation and network organization: a functional near-infrared spectroscopy study in healthy adults.Frontiers in neurology · 2026Trial
- The effect of cold needle on the development of pain and ecchymosis in subcutaneous heparin injection in adults: a prospective, randomised controlled study.Irish journal of medical science · 2025Trial
- Article
- Development of a Low-Cost Portable Exhaled Breath Ammonia Detector for Supplementary Five-Stage CKD Classification Using Embedded Threshold Logic.Sensors (Basel, Switzerland) · 2026Article
- Virtual Reality for Managing Procedural Pain and Distress in Paediatrics: A Scoping Review.Journal of clinical nursing · 2026Article
- Virtual reality for managing pain and fear and anxiety during pediatric needle procedures: an umbrella review.Clinical and experimental pediatrics · 2026Article
- Immediate and Short-Term Effects of Nature-Based Immersive Virtual Reality During Dry Needling: A Single-Blinded Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Tralokinumab as a cost-saving treatment option for adults and adolescents with moderate-to-severe atopic dermatitis enrolled in US health insurance plans: a budget impact analysis.Journal of comparative effectiveness research · 2026Article
- Fabrication of Microneedle Patches by Suspension Casting of Drugs in Organic Solvents.Pharmaceutics · 2026Article
- A Stroke Mimic Driven by Fear: Nonketotic Hyperglycemic Hemichorea in a Patient With Needle Phobia.Cureus · 2026Article
- 'Navigating Tiny Paths, Overcoming Huge Hurdles': The Struggles of Nurses in Paediatric Intravenous Intervention.Nursing open · 2026Article
- Floss-based vaccination targets the gingival sulcus for mucosal and systemic immunization.Nature biomedical engineering · 2026Article
- Effect of Vibration Anesthesia on Injection-Related Pain: A Prospective Crossover Study [Response to Letter].Journal of pain research · 2026Article
- Effect of Vibration Anesthesia on Injection-Related Pain: A Prospective Crossover Study.Journal of pain research · 2026Article
- Factors associated with documented distress during venipuncture in routine health checkups.Frontiers in psychiatry · 2026Article
- Value, development challenges, and strategies for gaining internal endorsement of digitally connected subcutaneous drug delivery devices: a survey of pharmaceutical stakeholders.Frontiers in digital health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Needle phobia is an overlooked condition that affects virtually all medical procedures. Our study aimed to identify how commonly needle phobia is experienced, its underlying reasons, impacts, and potential mitigation strategies. A global survey was conducted in a general adult population using a questionnaire based on a targeted literature review that identified under-researched areas. The 21-item questionnaire was completed on a secure, web-based survey platform. Statistical analyses and models were utilized to identify relationships between participant characteristics and needle phobia. Of the 2,098 participants enrolled in the study, 63.2% (n = 1,325) reported experiencing needle phobia, and rated the intensity of their fear as 5.7 (±2.6) on average on a scale from 0 (no fear) to 10 (very strong/unreasonable fear or avoidance). According to the logistic regression model, other medical fears (odds coefficient = 2.14) and family history (1.67) were the most important factors associated with needle phobia. General anxiety (96.1%) and pain (95.5%) were the most common reasons for needle fear. Of the participants experiencing needle phobia, 52.2% stated avoiding blood draws, followed by 49.0% for blood donations, and 33.1% for vaccinations. While 24.3% of participants have seen a therapist, most have never sought help. The majority have shared their fear with nurses (61.1%) or physicians (44.4%); however, the provider helpfulness was rated as 4.9 (±3.1) on average on a scale from 0 (unhelpful) to 10 (extremely helpful). Utilizing non-invasive alternatives (94.1%) and smaller needles (91.1%) were most commonly identified as potential device-related solutions to alleviate fear; distractions (92.1%) and relaxation techniques (91.7%) were the top non-device-related approaches. Our findings highlight the prevalent nature of needle phobia and provide insights into its etiology and effects on patient care. Clinician responses were not perceived as helpful, emphasizing the need to address needle phobia, and improve patient experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.