Evidence map›Paper›PMID 36409720›Full record

ArticleCellular reprogramming2022

Bcl11b and Atoh8 Coordinate Cellular Plasticity for Reprogramming and Transformation.

Mo-Fan Huang, Rachel Shoemaker, Dung-Fang Lee

Open access · greenAbstract readNews
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular reprogramming, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mo-Fan HuangDepartment of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0002-2209-1236
Rachel ShoemakerDepartment of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0002-7511-0701
Dung-Fang LeeDepartment of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0003-2387-597X
The University of Texas MD Anderson Cancer Center · USRice University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation.

Indexed as

Cell PlasticityTranscription FactorsCell Transformation, NeoplasticCellular ReprogrammingHumansRepressor ProteinsTumor Suppressor ProteinsBCL11B protein, humanRepressor ProteinsTranscription FactorsTumor Suppressor Proteinscellular plasticityreprogrammingsingle-celltransformation

Identifiers

PMID36409720
PMCPMC9805845
OpenAlexW4309495368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.