Evidence map›Paper›PMID 36409551›Full record

ArticleJournal of feline medicine and surgery2022

Otitis media and interna with or without polyps in cats: association between meningeal enhancement on postcontrast MRI, cerebrospinal fluid abnormalities, and clinician treatment choice and outcome.

Guillaume F Dutil, Julien Guevar, Daniela Schweizer, Petra Roosje, Filip Kajin, Holger A Volk, Nick J Grapes, Steven De Decker, Rodrigo Gutierrez-Quintana, Jad Abouzeid and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Guillaume F DutilDivision of Clinical Neurology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.ORCID 0000-0001-6295-5601
Julien GuevarDivision of Small Animal Surgery, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Daniela SchweizerDivision of Radiology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Petra RoosjeDivision of Dermatology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Filip KajinDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Germany.
Holger A VolkDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Germany.
Nick J GrapesDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, UK.ORCID 0000-0002-8849-5508
Steven De DeckerDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, UK.ORCID 0000-0002-2505-2152
Rodrigo Gutierrez-QuintanaSmall Animal Hospital, School of Veterinary Medicine, University of Glasgow, Glasgow, UK.ORCID 0000-0002-3570-2542
Jad AbouzeidDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Paul FreemanDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Kiterie Me FallerHospital for Small Animals, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, UK.ORCID 0000-0002-4525-7059
Veronika M SteinDivision of Clinical Neurology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Arianna MaioliniDivision of Clinical Neurology, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
University of Bern · CHUniversity of Cambridge · GBUniversity of London · GBUniversity of Veterinary Medicine Hannover, Foundation · DEUniversity of Edinburgh · GBUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the association between meningeal enhancement (MgE) and cerebrospinal fluid (CSF) analysis results, their individual association with bacteriology results from affected ear samples and whether these test results influenced clinicians' therapeutic choice in cats with otitis media and interna (OMI).

methodsThis was a multicentre retrospective study carried out over an 8-year period. Cats diagnosed with OMI, with or without a nasopharyngeal polyp, leading to peripheral vestibular signs were included. Only cats for which MRI with postcontrast T1-weighted sequences and CSF analyses available were included. Cats with intra-axial MRI lesions or empyema were excluded.

resultsFifty-eight cats met the inclusion criteria. MgE was reported in 26/58 cases, of which nine had an abnormal CSF result (increased total nucleated cell count [TNCC] or total protein); 32/58 cases had no MgE, of which 10 showed abnormal CSF results. There was no association between bacteriology results (external ear canal or bulla) and MgE or abnormal CSF results. CSF abnormalities were statistically significantly more common in acute cases (n = 16/37) than in chronic cases (n = 3/21; Fischer's test CONCLUSIONS AND RELEVANCE: No association was found between the CSF and MgE results. Furthermore, no association was found between MgE, CSF or bacteriology findings. In addition, abnormal CSF results might lead the clinician to treat with corticosteroids, but they did not have any impact on duration of antimicrobial treatment. CSF abnormalities were seen significantly less frequently in chronic cases. The outcome tended to be poorer when MgE was detected on MRI.

Indexed as

Cat DiseasesOtitis ExternaOtitis MediaAnimalsCatsRetrospective Studiescerebrospinal fluidMRI meningeal enhancementOtitis media and internaperipheral vestibular signs

Identifiers

PMID36409551
PMCPMC10812352
OpenAlexW4309514331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.