Evidence map›Paper›PMID 36409431›Full record

ArticleMolecular diversity2023

Pharmacophore modeling, molecular docking, and molecular dynamics studies to identify new 5-HT

Allana Faustino Martins, Luana Janaína de Campos, Martin Conda-Sheridan, Eduardo Borges de Melo

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular diversity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Allana Faustino MartinsTheoretical Medicinal and Environmental Chemistry Laboratory (LQMAT), Department of Pharmacy, Western Paraná State University (UNIOESTE), Cascavel, Paraná, Brazil.
Luana Janaína de CamposDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA.
Martin Conda-SheridanDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA.
Eduardo Borges de MeloTheoretical Medicinal and Environmental Chemistry Laboratory (LQMAT), Department of Pharmacy, Western Paraná State University (UNIOESTE), Cascavel, Paraná, Brazil. eduardo.b.de.melo@gmail.com.ORCID http://orcid.org/0000-0002-7455-1820

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some important atypical antipsychotic drugs target the serotonergic receptor 2A (5-HT

Indexed as

Antipsychotic AgentsHumansLigandsMolecular Docking SimulationMolecular Dynamics SimulationPharmacophoreProtein BindingSerotoninAntipsychotic AgentsLigandsSerotonin5-HT2AR antogonistsAutism spectrum disorder (ASD)Molecular dynamicsMolecular modelingVirtual screening

Identifiers

PMID36409431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.