ArticleVeterinary medicine and science2023
Manganese-methionine chelate improves antioxidant activity, immune system and egg manganese enrichment in the aged laying hens.
Article in Veterinary medicine and science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Oxidative homeostasis and survival instincts of chicken egg, embryo and adult.Poultry science · 2026Review
- Maternal Supplementation of Collagen Peptide Chelated Trace Elements Enhances Skeletal Muscle Development in Chicks.Biological trace element research · 2025Article
- Effects of Calcium Carbonate Particle Size, Phytase and Midnight Feeding on Performance, Egg and Bone Quality and Blood Parameters in Laying Hens.Veterinary medicine and science · 2025Article
- Manganese deficiency or dietary manganese(III) oxide nanoparticle supplementation: consequences for hematology, and intestinal and brain immunity in rats.Frontiers in immunology · 2025Article
- Mechanism and application of yeast and its culture in regulating intestinal antioxidant defense in ruminants.Frontiers in veterinary science · 2025Review
- Cholecalciferol combined with Satureja rechingeri essential oils improves growth performance and immune response of broiler chickens.Veterinary medicine and science · 2024Article
- Influence of Dietary Addition of Mineral Shungite andAnimals : an open access journal from MDPI · 2023Article
- Worldwide Research Trends for Chelates in Animal Science: A Bibliometric Analysis.Animals : an open access journal from MDPI · 2023Article
- Manganese-methionine chelate improves antioxidant activity, immune system and egg manganese enrichment in the aged laying hens.Veterinary medicine and science · 2023Article
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3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt has been reported that supplementation of manganese (Mn) could alleviate the negative effects of age on egg quality in laying hens. However, limited information is available on compensatory ways in order to reduce the adverse effects of hen age on health and Mn deposition in the body.
objectivesThe objectives were to investigate the effect of organic and inorganic sources of Mn on antioxidant activity, immune system, liver enzymes, shell quality and Mn deposition in the tissues of older laying hens.
methodsA total of 250, 80-week-old Leghorn laying hens (w36) were allocated into five treatment groups with five replications in a completely randomised design. Treatments were control (without Mn supplementation), 100% Mn sulphate, 75% Mn sulphate + 25% organic Mn chelate, 50% Mn sulphate + 50% organic Mn chelate and 25% Mn sulphate + 75% organic Mn chelate.
resultsThe groups fed 50 and 75% organic Mn chelate exhibited the lowest feed conversion ratio, as well as the maximum laying percentage, and egg weight and mass. Except to those fed 75% Mn sulphate, the hens received Mn supplements either as organic or inorganic, had higher immunoglobulin G and M compared with the control (p < 0.05). A significant elevation in the values of superoxide dismutase was observed in the hens receiving 50 and 75% organic Mn chelate when compared with the other treatments. The ALP activity decreased with increasing organic Mn chelate. Mn supplementation, either as organic or inorganic, increased Mn deposition in bone, egg yolk and shell, serum and liver.
conclusionDietary supplementation with 50-75% Mn-methionine has the potential to replace Mn-sulphate in laying hens' diet for improving eggshell quality, Mn deposition in the eggshell, antioxidant capacity and immune response, as well as improving laying performance, egg weight and feed conversion ratio.
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