Evidence map›Paper›PMID 36409110›Full record

ArticleJournal of virology2022

Porcine Circovirus Type 2 Hijacks Host IPO5 to Sustain the Intracytoplasmic Stability of Its Capsid Protein.

Cui Lin, Jingyu Hu, Yadong Dai, Huandong Zhang, Kang Xu, Weiren Dong, Yan Yan, Xiran Peng, Jiyong Zhou, Jinyan Gu

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Cui LinKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Jingyu HuKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Yadong DaiKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Huandong ZhangKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Kang XuKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Weiren DongKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Yan YanKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Xiran PengKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.
Jiyong ZhouKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.ORCID 0000-0002-8852-1227
Jinyan GuKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang Universitygrid.13402.34 Center for Veterinary Sciences, Hangzhou, China.ORCID 0000-0002-9763-9569
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear entrance and stability of porcine circovirus type 2 (PCV2), the smallest virus in mammals, are crucial for its infection and replication. However, the mechanisms are not fully understood. Here, we found that the PCV2 virion maintains self-stability via the host importin 5 (IPO5) during infection. Coimmunoprecipitation combined with mass spectrometry and glutathione

Indexed as

Capsid ProteinsCircoviridae InfectionsCircovirusKaryopherinsSwine DiseasesAnimalsCapsidSwineVirionCapsid ProteinsKaryopherinscapsid proteinIPO5nuclear importporcine circovirusprotein degradation

Identifiers

PMID36409110
PMCPMC9749456
OpenAlexW4309518308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.