Evidence map›Paper›PMID 36409063›Full record

ArticleeLife2022

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Matthew T Parker, Beth K Soanes, Jelena Kusakina, Antoine Larrieu, Katarzyna Knop, Nisha Joy, Friedrich Breidenbach, Anna V Sherwood, Geoffrey J Barton, Sebastian M Fica and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. RNA regulation in plants.Science China. Life sciences · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. RNA Triple Helices: From Structures and Mechanisms to Therapeutic Targets.International journal of biological sciences · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. International journal of molecular sciences · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Matthew T ParkerSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-0891-8495
Beth K SoanesCentre for Plant Sciences, School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Jelena KusakinaCentre for Plant Sciences, School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Antoine LarrieuCentre for Plant Sciences, School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Katarzyna KnopSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-2636-9450
Nisha JoySchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Friedrich BreidenbachSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-9610-1927
Anna V SherwoodSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0001-7153-8420
Geoffrey J BartonSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-9014-5355
Sebastian M FicaDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Brendan H DaviesCentre for Plant Sciences, School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Gordon G SimpsonSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0001-6744-5889
University of Dundee · GBUniversity of Leeds · GBJames Hutton Institute · GBUniversity of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M000338/1Biotechnology and Biological Sciences Research Council BB/M004155/1Biotechnology and Biological Sciences Research Council BB/M010066/1Biotechnology and Biological Sciences Research Council BB/T007222/1Biotechnology and Biological Sciences Research Council BB/V010662/1Biotechnology and Biological Sciences Research Council BB/W002302/1Biotechnology and Biological Sciences Research Council BB/W007673/1Biotechnology and Biological Sciences Research Council BB/W007967/1Wellcome TrustWellcome Trust 220212/Z/20/Z
6 · The paper itself

Abstract

Alternative splicing of messenger RNAs is associated with the evolution of developmentally complex eukaryotes. Splicing is mediated by the spliceosome, and docking of the pre-mRNA 5' splice site into the spliceosome active site depends upon pairing with the conserved ACAGA sequence of U6 snRNA. In some species, including humans, the central adenosine of the AC

Indexed as

ArabidopsisRNA PrecursorsHumansRNA, Small NuclearRNA Splice SitesRNA SplicingSpliceosomesRNA PrecursorsRNA, Small NuclearRNA Splice SitesU6 small nuclear RNAambient temperatureA. thalianaC. eleganschromosomesD. melanogasterepitranscriptomeflowering timegene expressiongeneticsgenomicshumanm6Asplicingzebrafish

Identifiers

PMID36409063
PMCPMC9803359
OpenAlexW4309514325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.