Evidence map›Paper›PMID 36408782›Full record

SynthesisInternational wound journal2023

Effect of educational interventions on wound healing in patients with venous leg ulceration: A systematic review and meta-analysis.

Jasmin Bossert, Johannes A Vey, Lars Piskorski, Thomas Fleischhauer, Sinclair Awounvo, Joachim Szecsenyi, Jonas Senft

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. The Impact of a Multidisciplinary Patient Education Program on Venous Leg Ulcer Healing: A Randomised Controlled Trial.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Trial
  5. Outpatient care for venous leg ulceration in Germany: A retrospective claims data analysis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Article
  6. Article
  7. Management of Chronic Health Situations.Healthcare (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jasmin BossertDepartment of General Practice and Health Service Research, University Hospital Heidelberg, Heidelberg, Germany.
Johannes A VeyInstitute of Medical Biometry, University Hospital Heidelberg, Heidelberg, Germany.
Lars PiskorskiDepartment of General Practice and Health Service Research, University Hospital Heidelberg, Heidelberg, Germany.
Thomas FleischhauerDepartment of General Practice and Health Service Research, University Hospital Heidelberg, Heidelberg, Germany.
Sinclair AwounvoInstitute of Medical Biometry, University Hospital Heidelberg, Heidelberg, Germany.
Joachim SzecsenyiDepartment of General Practice and Health Service Research, University Hospital Heidelberg, Heidelberg, Germany.
Jonas SenftDepartment of General Practice and Health Service Research, University Hospital Heidelberg, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEZimmer Biomet (Germany) · DE

Funding

Innovationsfonds des Gemeinsamen Bundesausschusses 01VSF19043
6 · The paper itself

Abstract

Educational interventions for patients with venous leg ulceration (VLU) may promote adherence and self-management, however, their effect on wound healing is unclear. A systematic literature search was performed and randomised controlled trials with a focus on educational interventions were included. Wound healing was analysed by assessing wound healing rate, ulcer size, and the PUSH Score. Additional outcomes comprised pain, quality of life, and functional ability. The study protocol for this work is registered at PROSPERO 2020 (ID: CRD42021286152). Nine studies were included in this meta-analysis. The odds ratio for wound healing was 1.91 (95% CI, 0.99-3.67, P = .053) in favour of educational interventions compared to usual care. Ulcer size reduction was higher (MD: -7.22; 95% CI, -11.91 to -2.53, P = .003) in patients following educational interventions. Included studies also showed significant effects on pain, quality of life, and functional analysis, though no quantitative synthesis was feasible. The overall risk of bias showed some concerns. Educational interventions aim to actively involve patients in their treatment, thereby appearing to be able to have a positive impact on wound healing within 12 weeks. Consequently, integrating educational approaches to routine wound care may be a promising strategy to improve treatment of VLU.

Indexed as

LegVaricose UlcerHumansPainQuality of LifeUlcerWound Healingchronic woundeducational interventionsprimary carevenous leg ulcerwound healing

Identifiers

PMID36408782
PMCPMC10088831
OpenAlexW4309514849

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.