ArticleHypertension (Dallas, Tex. : 1979)2023
Relation of Pulse Wave Velocity to Contemporaneous and Historical Blood Pressure in Female Twins.
Article in Hypertension (Dallas, Tex. : 1979), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Associated factors of elastic and stiffening components of pulse pressure based on 45 517 database of 24 h ambulatory blood pressure monitoring.Journal of human hypertension · 2026Article
- Arterial stiffening in children with early chronic kidney disease is associated with blood pressure but not decline in kidney function: a longitudinal study from the HOT-KID cohort.Pediatric nephrology (Berlin, Germany) · 2026Article
- Higher adherence to (poly)phenol-rich diet is associated with lower CVD risk in the TwinsUK cohort.BMC medicine · 2025Article
- Continuous measurement of pulse arrival time for identification of blood pressure changes in patients undergoing hemodialysis-a feasibility study.Clinical kidney journal · 2025Article
- Is It Time to Abandon the Kidney-Centered View on the Origin of Primary Hypertension?Hypertension (Dallas, Tex. : 1979) · 2025Review
- A cost-effective, machine learning-driven approach for screening arterial functional aging in a large-scale Chinese population.Frontiers in public health · 2024Article
- BOLD cardiorespiratory pulsatility in the brain: from noise to signal of interest.Frontiers in human neuroscience · 2023Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAn association between blood pressure and aortic stiffness is well known, but ambiguity remains as to whether one precedes the other. This study aimed to investigate the association of aortic stiffness with contemporaneous versus historic blood pressure and direction of causality between aortic stiffening and hypertension in female twins.
methodsAortic stiffness, measured by carotid-femoral pulse wave velocity (PWV), and mean arterial pressure (MAP) was recorded in 2037 female TwinsUK participants (mean age: 62.4±9.7 years) at a single time point. A subset of 947 participants had repeat PWV and MAP measures (mean interval 5.5±1.7 years) with additional historic MAP (mean interval 6.6±3.3 years before baseline).
resultsCross-sectional multivariable linear regression analysis confirmed PWV significantly associated with age and MAP. In longitudinal analysis, annual progression of PWV was not associated with historic MAP (standardized beta coefficient [β]=-0.02,
conclusionsProgression of aortic stiffness associates more strongly with contemporaneous MAP compared with historic MAP. In contrast, progression of MAP is associated with prior arterial stiffness. These findings suggest a bidirectional relationship between arterial stiffness and blood pressure, and that lowering blood pressure may prevent a cycle of arterial stiffening and hypertension.
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Registered trials
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