Evidence map›Paper›PMID 36408534›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2022

Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods.

Steven M Lewis, Mackenzie K Callaway, Camila O Dos Santos

Open access · greenAbstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Breast Cancer: Extracellular Matrix and Microbiome Interactions.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Using Organoids to Tap Mammary Gland Diversity for Novel Insight.Journal of mammary gland biology and neoplasia · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Introduction to the thematic issue: Recognition of women leaders in Science.Experimental biology and medicine (Maywood, N.J.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Steven M LewisCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Mackenzie K CallawayCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Camila O Dos SantosCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.ORCID 0000-0002-3999-9523
Cold Spring Harbor Laboratory · US

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI David A Tuveson · 1987 to 2026
$118.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008444 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI FROHMAN, MICHAEL A. · 1992 to 2024
$12.6M
Probing the role of epigenomics in Brca1-deficient mammary tumors.R01CA248158 · NCI · COLD SPRING HARBOR LABORATORY · PI DOS SANTOS, CAMILA · 2020 to 2024
$2.2M
Defining the cellular and molecular effects of aging and age of pregnancy on breast tissue homeostasis and cancer initiationR01AG069727 · NIA · COLD SPRING HARBOR LABORATORY · PI DOS SANTOS, CAMILA · 2020 to 2024
$1.8M
NCI NIH HHS P30 CA045508NCI NIH HHS R01 CA248158NIA NIH HHS R01 AG069727NIGMS NIH HHS T32 GM008444
6 · The paper itself

Abstract

While mouse models and two-dimensional (2D) cell culture systems have dominated as research tools for cancer biology, three-dimensional (3D) cultures have gained traction as a new approach that retains features of

Indexed as

NeoplasmsSpheroids, CellularAnimalsCoculture TechniquesDisease Models, AnimalMiceOrganoidsTumor Cells, CulturedBreast cancerextracellular matrixhigh-throughput drug testingmammary gland developmentorganoidspersonalized medicine

Identifiers

PMID36408534
PMCPMC9899987
OpenAlexW4309509362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.