ArticleFrontiers in neurology2022
Performance in information processing speed is associated with parietal white matter tract integrity in multiple sclerosis.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparing cognitive impairment using MACFIMS in patients with multiple sclerosis and healthy controls: a systematic review and meta-analysis.BMC neurology · 2024Pooled it
- Information processing speed modulation by electrical brain stimulation in multiple sclerosis: towards individually tailored protocols.Brain communications · 2025Trial
- Retinal layers prognosticate cognitive progression independent of relapse activity in multiple sclerosis.Journal of neurology · 2026Article
- Theory of Mind and Information Processing Speed in Multiple Sclerosis: Associations With Personality Traits.Brain and behavior · 2026Article
- Negative impact of hippocampal radiotherapy dose on memory function in patients with brain metastases.Neuro-oncology practice · 2026Article
- Traumatic Brain Injury-Induced White Matter Disruption and Its Impact on Information Processing Speed-Theoretical and Clinical Implications: A Selective Review.Journal of clinical medicine · 2026Review
- Clinical and MRI substrates of Symbol Digit Modalities Test impairment in multiple sclerosis patients with an adult- and late-onset.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- Temporally Defined Brain Network Activation Associated With Slowed Information Processing Speed in Multiple Sclerosis.Human brain mapping · 2026Article
- Global functional connectivity reorganization reflects cognitive processing speed deficits and fatigue in multiple sclerosis.European journal of neurology · 2025Article
- Cross-sectional and longitudinal evaluation of white matter microstructure damage and cognitive correlations by automated fibre quantification in relapsing-remitting multiple sclerosis patients.Brain imaging and behavior · 2024Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The Symbol Digit Modalities Test (SDMT) is most frequently used to test processing speed in patients with multiple sclerosis (MS). Functional imaging studies emphasize the importance of frontal and parietal areas for task performance, but the influence of frontoparietal tracts has not been thoroughly studied. We were interested in tract-specific characteristics and their association with processing speed in MS patients. Methods: Diffusion tensor imaging was obtained in 100 MS patients and 24 healthy matched controls to compare seed-based tract characteristics descending from the superior parietal lobule [Brodman area 7A (BA7A)], atlas-based tract characteristics from the superior longitudinal fasciculus (SLF), and control tract characteristics from the corticospinal tract (CST) and their respective association with ability on the SDMT. Results: Patients had decreased performance on the SDMT and decreased white matter volume (each Conclusions: Processing speed in MS is associated with the structural integrity of frontoparietal white matter tracts.
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