ArticleFrontiers in neurology2022
The predictive role of systemic inflammation response index in the prognosis of traumatic brain injury: A propensity score matching study.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Intracranial pressure, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, C-reactive protein, and D-dimer mortality predictors in isolated severe traumatic brain injury.Surgical neurology international · 2026Article
- Elevated WBC/HDL Ratio Predicts Poststroke Functional Prognosis.Brain and behavior · 2025Article
- Article
- Association between traumatic brain injury and risk of developing infections in the central nervous system and periphery.Metabolic brain disease · 2025Review
- Predictive value of hematologic indices on weaning from mechanical ventilation and 30-day mortality in patients with traumatic brain injury in an intensive care unit: A retrospective analysis of MIMIC-IV data.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Development and validation of a nomogram for predicting mortality in patients with acute severe traumatic brain injury: A retrospective analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- A nonlinear relationship between systemic inflammation response index and short-term mortality in patients with acute myocardial infarction: a retrospective study from MIMIC-IV.Frontiers in cardiovascular medicine · 2023Article
- Association between the systemic inflammation response index and serum uric acid in acute traumatic brain injury: a cross-sectional study.Frontiers in neurologyArticle
- Association between Systemic Immune-Inflammation Index and Systemic Inflammation Response Index and Outcomes of Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.Annals of Indian Academy of NeurologyReview
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Authors and funding
9 authors.
Funding
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Abstract
Background: We aimed to evaluate the predictive power of systemic inflammation response index (SIRI), a novel biomarker, to predict all-cause mortality in patients with traumatic brain injury (TBI) in the intensive care unit (ICU). Methods: Clinical data were retrieved from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Kaplan-Meier (KM) methods and cox proportional hazard models were performed to examine the association between SIRI and all-cause mortality. The predictive power of SIRI was evaluated compared to other leukocyte-related indexes including neutrophils, lymphocytes, monocytes and white blood cells (WBC) by the Receiver Operating Characteristic (ROC)curve for 30-day mortality. In addition, propensity score matching (PSM) was conducted to reduce confounding. Results: A total of 350 TBI patients were enrolled overall in our study. The optimal cutoff point of SIRI was determined at 11.24 × 10 Conclusion: It was suggested that TBI patients with high SIRI level would suffer from a high risk of 30-day, in-hospital and 365-day mortality. SIRI is a promising inflammatory biomarker for predicting TBI patients' prognosis with relatively better predictive power than other single indicators related to peripheral differential leukocyte counts.
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