ArticleFrontiers in neuroscience2022
Slow, deep breathing intervention improved symptoms and altered rectal sensitivity in patients with constipation-predominant irritable bowel syndrome.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- The effects of different exercise interventions on clinical outcomes of irritable bowel syndrome and their potential mechanisms: a systematic review and network meta-analysis.Frontiers in immunology · 2026Pooled it
- The effects of heart rate variability biofeedback on functional gastrointestinal disorders: a scoping review.Frontiers in physiology · 2025Pooled it
- Research on the mechanism of core acupoints in electroacupuncture for functional constipation based on data mining and network acupuncture.Frontiers in medicine · 2024Pooled it
- Noninvasive electrical neuromodulation involving vagus nerve mechanism for functional constipation and irritable bowel syndrome with constipation.Therapeutic advances in gastroenterology · 2026Review
- Digital and Conventional Behavioral Therapies for Neurogastroenterology and Motility Disorders.Current gastroenterology reports · 2025Review
- Comparing biofeedback device vs diaphragmatic breathing for bloating relief: A randomized controlled trial.Open medicine (Warsaw, Poland) · 2025Article
- A primer for the gastroenterology provider on psychosocial assessment of patients with disorders of gut-brain interaction.Neurogastroenterology and motility · 2024Review
- Effect of Pilates exercises on symptoms of irritable bowel syndrome in women: a randomized controlled trial.Archives of physiotherapyArticle
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim: Limited treatment options have been shown to alter the natural course of irritable bowel syndrome (IBS). Slow, deep breathing (SDB) is a common pain self-management intervention. This pilot study aimed to explore the impact of SDB on measures of autonomic and anorectal functions as well as patient-reported symptoms in constipation-predominant IBS (IBS-C). Methods: Eighty-five IBS-C patients were enrolled in this study and randomly assigned to the experimental group (Group A, Results: At baseline, no differences were found between Groups A and B. The IBS-SSS score and its five sub-scores of Group B patients were significantly higher at week 6 than those of Group A patients (all Conclusion: We found that a 6-week SDB intervention improved symptoms and altered rectal sensation in IBS-C patients. Moreover, SDB enhanced vagal activity. These findings suggest that the effect of SDB on IBS-C may be due to mechanisms involving autonomic responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.