Evidence map›Paper›PMID 36408400›Full record

ReviewFrontiers in neuroscience2022

Calcium imaging: A versatile tool to examine Huntington's disease mechanisms and progression.

Joshua Barry, Allison Peng, Michael S Levine, Carlos Cepeda

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. LPS-induced inflammation differentially affects endogenous CaMolecular medicine (Cambridge, Mass.) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joshua BarryIntellectual and Developmental Disabilities Research Center (IDDRC), Semel Institute for Neuroscience and Human Behavior, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Allison PengIntellectual and Developmental Disabilities Research Center (IDDRC), Semel Institute for Neuroscience and Human Behavior, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Michael S LevineIntellectual and Developmental Disabilities Research Center (IDDRC), Semel Institute for Neuroscience and Human Behavior, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Carlos CepedaIntellectual and Developmental Disabilities Research Center (IDDRC), Semel Institute for Neuroscience and Human Behavior, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
University of California, Los Angeles · USIntel (United States) · US

Funding

Cortical Pathophysiology in Mouse Models of Huntington's DiseaseR01NS096994 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEVINE, MICHAEL S. · 2017 to 2020
$2.0M
NINDS NIH HHS R01 NS096994
6 · The paper itself

Abstract

Huntington's disease (HD) is a fatal, hereditary neurodegenerative disorder that causes chorea, cognitive deficits, and psychiatric symptoms. It is characterized by accumulation of mutant Htt protein, which primarily impacts striatal medium-sized spiny neurons (MSNs), as well as cortical pyramidal neurons (CPNs), causing synapse loss and eventually cell death. Perturbed Ca

Indexed as

calcium imagingfiber photometryHuntington’s diseaseminiscopetwo-photon microscopy (2-PM)

Identifiers

PMID36408400
PMCPMC9669372
OpenAlexW4307995048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.