Evidence map›Paper›PMID 36408379›Full record

ArticleFrontiers in neuroscience2022

Prefrontal cortex neural activity predicts reduction of non-suicidal self-injury in adolescents with major depressive disorder: An event related potential study.

Huishan Liu, Yujiao Wen, Xiumei Liang, Yifan Xu, Dan Qiao, Chunxia Yang, Min Han, Hong Li, Tian Ren, Xuemin Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  12. [Advances in the electrophysiological research on neurocognitive function in adolescents with non-suicidal self-injury].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Huishan LiuDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Yujiao WenDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Xiumei LiangDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Yifan XuDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Dan QiaoDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Chunxia YangDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Min HanDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Hong LiDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Tian RenDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Xuemin ZhangDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Gaizhi LiDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Zhifen LiuDepartment of Psychiatry, The First Hospital of Shanxi Medical University, Taiyuan, China.
Shanxi Medical University · CNFirst Hospital of Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-suicidal self-injury (NSSI) is common in adolescent MDD, which is also a risk factor for suicide. However, there is few research on biomarkers and predictors about treatment response of NSSI. The purpose of this study was to find the difference of P300 between adolescent MDD with NSSI and healthy controls, and to explore whether the baseline electrophysiological level can predict the change of NSSI after treatment. Methods: We collected 62 first-episode drug-naïve MDD adolescents with NSSI (MDD with NSSI group) and 44 healthy controls (HC group). The demographic data, HAMD score, self-injury frequency and electrophysiological level of NSSI group and HC group were collected. The HAMD score, frequency of NSSI in was also collected after 8 weeks of antidepressant treatment. Results: Compared to HC, the latency of the N2, P3a, and P3b components were significantly prolonged, whereas the amplitude of P3a and P3b were decreased in the MDD with NSSI group ( Conclusion: P3b at baseline can be used as potential predictor for the reduction of NSSI in adolescent MDD.

Indexed as

adolescentERPmajor depressive disordernon-suicidal self-injury behaviorP300

Identifiers

PMID36408379
PMCPMC9671107
OpenAlexW4308414503

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.