Evidence map›Paper›PMID 36408134›Full record

ArticleFrontiers in oncology2022

The Global research of protein post-translational modifications in the cancer field: A bibliometric and visualized study.

Ruixia Ma, Meigui Zhang, Jiahui Xi, Jing Li, Yinxia Ma, Binxiao Han, Tuanjie Che, Zhihui Ma, Jinhui Tian, Zhongtian Bai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruixia MaThe First School of Clinical Medicine; The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.
Meigui ZhangThe First School of Clinical Medicine; The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.
Jiahui XiThe First School of Clinical Medicine; The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.
Jing LiThe First School of Clinical Medicine; The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.
Yinxia MaThe Second Clinical Medical School, Lanzhou University, Lanzhou, China.
Binxiao HanGansu Institute of Medical Information, Institute of Gansu Medical Science Research, Lanzhou, China.
Tuanjie CheKey Laboratory of Functional Genomic and Molecular Diagnosis of Gansu Province, Lanzhou, China.
Zhihui MaSchool of Mathematics and Statistics, Lanzhou University, Lanzhou, China.
Jinhui TianEvidence-Based Medicine Center School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Zhongtian BaiThe First School of Clinical Medicine; The First Hospital of Lanzhou University, Lanzhou University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Protein post-translational modifications (PTMs) are closely associated with tumorigenesis, targeting PTMs of key proteins might be the focus of antitumor drug discovery. This study aimed to analyze the research progress on protein PTMs in tumorigenesis by performing qualitative and quantitative evaluations. Methods: The Web of Science Core Collection was selected as the database, and Science Citation Index Expanded was selected as the citation index. Visualization tools such as VOSviewer, CiteSpace, HistCite, and Online Analysis Platform of Bibliometrics were used to deeply explore the information of the retrieved research papers and analyze them in terms of research trends and main aspects of research. Results: The search yielded 3777 relevant articles. The results showed that the total number of PTMs related papers in cancer field has been increasing annually, with the largest number of papers published in the United States of America. The co-word cluster analysis showed that the research on PTMs and tumorigenesis was primarily focused on the following four areas, mechanism, histone, P53, key Technologies. Tumor metabolism, autophagy, and protein-protein interaction, histone ubiquitination have become new research topics. Conclusion: This study provides an important reference for the research direction and selection of topics of interest in the PTMs of cancer field.

Indexed as

bibliometricscitespacehistciteknowledge graphpost-translational modificationtumorVOSviewer

Identifiers

PMID36408134
PMCPMC9670177

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.