Evidence map›Paper›PMID 36408098›Full record

ArticleFrontiers in aging neuroscience2022

Six month lower-leg mechanical tactile sensory stimulation alters functional network connectivity associated with improved gait in older adults with peripheral neuropathy - A pilot study.

Chun Liang Hsu, Brad Manor, Ikechkwu Iloputaife, Lars I E Oddsson, Lewis Lipsitz

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06959277 (Balance4Mobility), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06959277 narecruitingnot on this mapstarted 2025, after this paper: background citation

Balance4Mobility: Effects of Walkasins Use on Clinical Outcomes of Gait and Balance Function in Individuals With Peripheral Neuropathy and Balance Problems - A Randomized Control Trial

TypeinterventionalSponsorRxFunction Inc.Ran2025 to 2027Enrolled200ConditionsPeripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathy With Type 2 Diabetes, Balance Control in ElderlyArmsWalkasins, Fall Prevention Training
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Chun Liang HsuHebrew SeniorLife, Hinda and Arthur Marcus Institute for Aging Research, Roslindale, MA, United States.
Brad ManorHebrew SeniorLife, Hinda and Arthur Marcus Institute for Aging Research, Roslindale, MA, United States.
Ikechkwu IloputaifeHebrew SeniorLife, Hinda and Arthur Marcus Institute for Aging Research, Roslindale, MA, United States.
Lars I E OddssonDivision of Rehabilitation Science, Department of Rehabilitation Medicine, Medical School, University of Minnesota, Minneapolis, MN, United States.
Lewis LipsitzHebrew SeniorLife, Hinda and Arthur Marcus Institute for Aging Research, Roslindale, MA, United States.
Harvard University · USBeth Israel Deaconess Medical Center · USHebrew SeniorLife · USRxFunction (United States) · US

Funding

Personalized brain activity modulation to improve balance and cognition in elderly fallersR01AG059089 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI MANOR, BRADLEY D. · 2018 to 2022
$3.2M
A Wearable "Balance Booster" - Stepping Closer to the MarketR44AG040865 · NIA · RXFUNCTION, INC. · PI LEACH, JOSEPH DANIEL, ODDSSON, LARS I E · 2013 to 2014
$1.1M
Optimizing transcranial direct current stimulation (tDCS) to improve dual task gait and balance in older adultsR21AG064575 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI MANOR, BRADLEY D. · 2019 to 2020
$403k
NIA NIH HHS R01 AG059089NIA NIH HHS R21 AG064575NIA NIH HHS R44 AG040865
6 · The paper itself

Abstract

Foot sole somatosensory impairment associated with peripheral neuropathy (PN) is prevalent and a strong independent risk factor for gait disturbance and falls in older adults. Walkasins, a lower-limb sensory prosthesis, has been shown to improve gait and mobility in people with PN by providing afferent input related to foot sole pressure distributions

Indexed as

brain networksfMRIfunctional connectivityneuroprosthesisperipheral neuropathysensory substitution

Identifiers

PMID36408098
PMCPMC9669982
OpenAlexW4308419612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.