ArticleACS pharmacology & translational science2022
Structure-Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice.
Open access · greenAbstract read
In one paragraph
Article in ACS pharmacology & translational science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
15.4field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 85 citations in OpenAlex.
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- Syntheses and structures of two norpsilocin derivatives:Acta crystallographica. Section E, Crystallographic communications · 2026Article
- Cardiovascular safety of psilocybin in psychiatric practice: a narrative review.European journal of clinical pharmacology · 2026Review
- In-silico toxicity study of tryptamine, psilocin, psilocybin, N,N-dimethyltryptamine, 5'-methoxy-N,N-dimethyltryptamine and O-acetylpsilocin.Archives of toxicology · 2026Article
- Synthesis and Biological Evaluation of 4‑Bromo-ACS omega · 2026Article
- Preclinical models for evaluating psychedelics in the treatment of major depressive disorder.British journal of pharmacology · 2026Review
- Serotonin Transporter Blockade Reduces the Psychedelic-Like Effects of 4-Methoxy-ACS chemical neuroscience · 2026Article
- Short- and Long-Acting Psychedelics: Structure-Activity Relationships, Pharmacology, and Implications for Neuropsychiatric Therapeutics.ACS chemical neuroscience · 2026Review
- Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature.Ecology and evolution · 2026Article
- Effects of psilocybin and chronic mild stress on microglial activation in rat spinal cord: an ex vivo analysis.Pharmacological reports : PR · 2026Article
- Pharmacodynamic effects and plasma pharmacokinetics of N, N-dimethyltryptamine after intranasal versus subcutaneous administration in male rats.Psychopharmacology · 2026Article
- Therapeutic Effects of Low-Dose Psilocybin in Depression and Other Mental Disorders: A Systematic Review.Psychedelic medicine (New Rochelle, N.Y.) · 2026Review
- The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects.Molecular psychiatry · 2026Article
- No evidence of immediate or persistent analgesic effect from a single dose of psilocybin in three mouse models of pain.Nature communications · 2026Article
- Psychedelic Drugs Rediscovered-In Silico Study of Potential Fetal Exposure to Analogues of Psychedelic Drugs During Pregnancy.Molecules (Basel, Switzerland) · 2026Article
- Psychedelic Drug Checking: Analytical and Strategic Challenges in Harm Reduction for Classic Psychedelics.Current topics in behavioral neurosciences · 2026Review
- The ABCs of psychedelics: a preclinical roadmap for drug discovery.Trends in pharmacological sciences · 2025Review
- Psychedelic-like effects induced by 2,5-dimethoxy-4-iodoamphetamine, lysergic acid diethylamide, and psilocybin in male and female C57BL/6J mice.Psychopharmacology · 2025Article
- Rapid, Open-Source, and Automated Quantification of the Head Twitch Response in C57BL/6J Mice Using DeepLabCut and Simple Behavioral Analysis.ACS pharmacology & translational science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 2 countries.
Grant C GlatfelterDesigner Drug Research Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, Maryland 21224, United States.ORCID https://orcid.org/0000-0003-1011-9083
Eline PottieLaboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Campus Heymans, Ottergemsesteenweg 460, 9000 Ghent, Belgium.
John S PartillaDesigner Drug Research Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, Maryland 21224, United States.
Alexander M SherwoodUsona Institute, Madison, Wisconsin 53711, United States.ORCID https://orcid.org/0000-0003-0895-0791
Kristi KayloUsona Institute, Madison, Wisconsin 53711, United States.
Duyen N K PhamDepartment of Chemistry & Biochemistry, University of Massachusetts Dartmouth, North Dartmouth, Massachusetts 02747, United States.
Marilyn NaeemDepartment of Chemistry & Biochemistry, University of Massachusetts Dartmouth, North Dartmouth, Massachusetts 02747, United States.
Vamshikrishna Reddy SammetaDepartment of Chemistry & Biochemistry, University of Massachusetts Dartmouth, North Dartmouth, Massachusetts 02747, United States.
Stacie DeBoerDepartment of Chemistry, University of Wyoming, Laramie, Wyoming 82071, United States.
James A GolenDepartment of Chemistry & Biochemistry, University of Massachusetts Dartmouth, North Dartmouth, Massachusetts 02747, United States.
Elliott B HulleyDepartment of Chemistry, University of Wyoming, Laramie, Wyoming 82071, United States.ORCID https://orcid.org/0000-0002-2630-3689
Christophe P StoveLaboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Campus Heymans, Ottergemsesteenweg 460, 9000 Ghent, Belgium.ORCID https://orcid.org/0000-0001-7126-348X
Andrew R ChadeayneCaaMTech, Inc., Issaquah, Washington 98027, United States.
David R MankeDepartment of Chemistry & Biochemistry, University of Massachusetts Dartmouth, North Dartmouth, Massachusetts 02747, United States.ORCID https://orcid.org/0000-0002-2513-4801
Michael H BaumannDesigner Drug Research Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, Maryland 21224, United States.ORCID https://orcid.org/0000-0001-7758-1470
University of Massachusetts Dartmouth · USNational Institute on Drug Abuse · USGhent University · BEUniversity of Wyoming · USUsona Institute · US
Funding
Development of Dual Dopamine/Serotonin Releasing AgentsZ01DA000522 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI ROTHMAN, RICHARD · 2008 to 2008
$598kIntramural NIH HHS Z01 DA000522
Abstract
4-Phosphoryloxy-
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.