Evidence map›Paper›PMID 36407934›Full record

ArticleJournal of water process engineering2022

Biocatalyst developed with recovered iron-rich minerals enhances the biotransformation of SARS-CoV-2 antiviral drugs in anaerobic bioreactors.

Francisco J Mares-Carbajal, M Carolina Espinosa-Arzate, Luis A Ramírez-Montoya, Aurora M Pat-Espadas, J Ernesto Ramírez, J René Rangel-Mendez, Juan A Ascacio-Valdes, Cristóbal N Aguilar, Petia Mijaylova, Germán Buitrón and 1 more

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In one paragraph

Article in Journal of water process engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Francisco J Mares-CarbajalLaboratory for Research on Advanced Processes for Water Treatment, Engineering Institute, Campus Juriquilla, Universidad Nacional Autónoma de México (UNAM), Blvd. Juriquilla 3001, 76230 Querétaro, Mexico.
M Carolina Espinosa-ArzateLaboratory for Research on Advanced Processes for Water Treatment, Engineering Institute, Campus Juriquilla, Universidad Nacional Autónoma de México (UNAM), Blvd. Juriquilla 3001, 76230 Querétaro, Mexico.
Luis A Ramírez-MontoyaLaboratory for Research on Advanced Processes for Water Treatment, Engineering Institute, Campus Juriquilla, Universidad Nacional Autónoma de México (UNAM), Blvd. Juriquilla 3001, 76230 Querétaro, Mexico.
Aurora M Pat-EspadasCONACYT-UNAM Instituto de Geología, Estación Regional del Noroeste (ERNO), Luis D. Colosio y Madrid, Hermosillo, Sonora, Mexico.
J Ernesto RamírezUnidad Académica de Ingeniería I, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.
J René Rangel-MendezDivisión de Ciencias Ambientales, Instituto Potosino de Investigación Científica y Tecnológica, Camino a la Presa San José 2055, Lomas 4 Sección, 78216 San Luis Potosí, Mexico.
Juan A Ascacio-ValdesFacultad de Ciencias Químicas, Departamento de Investigación en Alimentos (DIA-UAdeC), Universidad Autónoma de Coahuila, Saltillo 25280, Coahuila, Mexico.
Cristóbal N AguilarFacultad de Ciencias Químicas, Departamento de Investigación en Alimentos (DIA-UAdeC), Universidad Autónoma de Coahuila, Saltillo 25280, Coahuila, Mexico.
Petia MijaylovaSubcoordinación de Tratamiento de Aguas Residuales, Instituto Mexicano de Tecnología del Agua, Paseo Cuauhnáhuac 8532, Progreso, Jiutepec 62550, Morelos, Mexico.
Germán BuitrónLaboratory for Research on Advanced Processes for Water Treatment, Engineering Institute, Campus Juriquilla, Universidad Nacional Autónoma de México (UNAM), Blvd. Juriquilla 3001, 76230 Querétaro, Mexico.
Francisco J CervantesLaboratory for Research on Advanced Processes for Water Treatment, Engineering Institute, Campus Juriquilla, Universidad Nacional Autónoma de México (UNAM), Blvd. Juriquilla 3001, 76230 Querétaro, Mexico.
Universidad Nacional Autónoma de México · MXUniversidad Autónoma de Coahuila · MXUniversidad Autónoma de Zacatecas "Francisco García Salinas" · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biotransformation of the SARS-CoV-2 antiviral drugs, ribavirin and tenofovir, was studied in methanogenic bioreactors. The role of iron-rich minerals, recovered from a metallurgic effluent, on the biotransformation process was also assessed. Enrichment of anaerobic sludge with recovered minerals promoted superior removal efficiency for both antivirals (97.4 % and 94.7 % for ribavirin and tenofovir, respectively) as compared to the control bioreactor lacking minerals, which achieved 58.5 % and 37.9 % removal for the same drugs, respectively. Further analysis conducted by liquid chromatography coupled to mass spectroscopy revealed several metabolites derived from the biotransformation of both antivirals. Interestingly, tracer analysis with

Indexed as

BiodegradationCircular economyEmerging contaminantsPharmaceuticalsWastewater

Identifiers

PMID36407934
PMCPMC9663753
OpenAlexW4309154235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.