ArticleDental research journal2022
Cytotoxicity and induced apoptosis of a new bioceramic cement containing simvastatin on stem cells from human exfoliated deciduous teeth.
Article in Dental research journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Osteogenic Potential of a Three-Phase Strontium- and Silicon-Doped Tricalcium Silicate Cement on Dental Pulp Stem Cells: An In Vitro Study.Clinical and experimental dental research · 2026Article
- Physical and drug- releasing properties of a cement containing simvastatin (SimCeram).BMC oral health · 2025Article
- Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study.International journal of clinical pediatric dentistry · 2024Article
- Histological Evaluation of Photobiomodulation and Calcium Aluminosilicate on Direct Pulp Capping of Dogs' Permanent Teeth.Journal of lasers in medical sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aims to compare cytotoxicity and induced apoptosis of a new bioceramic cement containing different concentrations of simvastatin on stem cells from human exfoliated deciduous teeth (SHED). Materials and Methods: This research was an Results: During 7 days, MTA, bioceramic cement, simvastatin 0.1 and 0.01 μM, and bioceramic cement containing 0.1 and 0.01 μM simvastatin increased ( Conclusion: After 7 days, the viability of the SHED in the presence of a new bioceramic cement containing 0.1 and 0.01 μM simvastatin was not compromised. Moreover, this cement showed superior results than MTA and provided an environment for cell proliferation. This finding appears to be due to the pharmacological effects of low concentrations of simvastatin.
Indexed as
Identifiers
36407772PMC9667492W4309660964What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.