Evidence map›Paper›PMID 36407553›Full record

ArticleFrontiers in nutrition2022

The oral bioaccessibility and gingival cytotoxicity of metal(loid)s in wild vegetables from mining areas: Implication for human oral health.

Wen Tian, Peng Gao, Da-Peng Zong, Jian-Jun Liu, Meng-Yan Zhang, Cheng-Chen Wang, Zhen-Xing Wang, Jian-Min Wang, You-Ya Niu, Ping Xiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Wen TianYunnan Province Innovative Research Team of Environmental Pollution, Food Safety, and Human Health, School of Ecology and Environment, Southwest Forestry University, Kunming, China.
Peng GaoDepartment of Environmental and Occupational Health, University of Pittsburgh School of Public Health, Pittsburgh, PA, United States.
Da-Peng ZongYunnan Province Innovative Research Team of Environmental Pollution, Food Safety, and Human Health, School of Ecology and Environment, Southwest Forestry University, Kunming, China.
Jian-Jun LiuYunnan Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Biomedical Engineering, Kunming Medical University, Kunming, China.
Meng-Yan ZhangYunnan Province Innovative Research Team of Environmental Pollution, Food Safety, and Human Health, School of Ecology and Environment, Southwest Forestry University, Kunming, China.
Cheng-Chen WangYunnan Province Innovative Research Team of Environmental Pollution, Food Safety, and Human Health, School of Ecology and Environment, Southwest Forestry University, Kunming, China.
Zhen-Xing WangSchool of Life Science, Southwest Forestry University, Kunming, China.
Jian-Min WangYunnan Rural Science and Technology Service Centre, Kunming, China.
You-Ya NiuSchool of Basic Medical Sciences, Hunan University of Medicine, Huaihua, China.
Ping XiangYunnan Province Innovative Research Team of Environmental Pollution, Food Safety, and Human Health, School of Ecology and Environment, Southwest Forestry University, Kunming, China.
Southwest Forestry University · CNHunan University · CNKunming Medical University · CNUniversity of Pittsburgh · USYunnan Provincial Science and Technology Department · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Heavy metal(loid)s are frequently detected in vegetables posing potential human health risks, especially for those grown around mining areas. However, the oral bioaccessibility and gingival cytotoxicity of heavy metals in wild vegetables remain unclear. Methods: In this study, we assessed the total and bioaccessible Cr, As, Cd, Pb, and Ni in four wild vegetables from mining areas in Southwest China. In addition, the cytotoxicity and underlying mechanisms of vegetable saliva extracts on human gingival epithelial cells (HGEC) were studied. Results: The Conclusion: Our results indicated that polluted vegetable intake caused toxic effects on human gingiva. The heavy metals in vegetables were not positively related to human health risks. Collectively, both bioaccessibility and toxic data should be considered for accurate risk assessment.

Indexed as

gingival cytotoxicityhealth riskheavy metal(loid)soral bioaccessibilitywild vegetables

Identifiers

PMID36407553
PMCPMC9670124
OpenAlexW4308020272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.