Evidence map›Paper›PMID 36407516›Full record

ArticleFrontiers in nutrition2022

The causal association between iron status and the risk of autism: A Mendelian randomization study.

Li Chen, Xingzhi Guo, Chen Hou, Peng Tang, Xin Zhang, Li Chong, Rui Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Iron dysregulation in the central nervous system: implications for autism spectrum disorder.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. [Advances in Mendelian randomization studies on autism spectrum disorder].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Li ChenDepartment of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Xingzhi GuoDepartment of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Chen HouDepartment of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Peng TangDepartment of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Xin ZhangDepartment of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Li ChongDepartment of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Rui LiDepartment of Geriatric Neurology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Shaanxi Provincial People's Hospital · CNNorthwestern Polytechnical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence indicates a connection between serum iron levels and autism, but the underlying causal association is yet unclear. Thus, we performed two-sample Mendelian randomization (MR) analysis to evaluate the causal link between iron status on autism, using genetic instruments (

Indexed as

autismferritinironMendelian randomizationtransferrin

Identifiers

PMID36407516
PMCPMC9669792
OpenAlexW4308416528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.