Evidence map›Paper›PMID 36407507›Full record

ArticleFrontiers in nutrition2022

Association of dietary intake of saturated fatty acids with hypertension: 1999-2018 National Health and Nutrition Examination Survey.

Ruoyu Gou, Yufan Gou, Jian Qin, Tingyu Luo, Qiannan Gou, Kailian He, Song Xiao, Ruiying Li, Tingjun Li, Jie Xiao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  5. The Impact of Diet and Sociodemographic Factors on Cardiovascular Health in University Students.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Ruoyu GouGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Yufan GouDepartment of Political Science and Administration, School of International Affairs and Public Administration, Ocean University of China, Qingdao, China.
Jian QinDepartment of Environmental and Occupational Health, School of Public Health, Guangxi Medical University, Nanning, China.
Tingyu LuoGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Qiannan GouDepartment of Food Science, Faculty of Veterinary and Agricultural, The University of Melbourne, Parkville, VIC, Australia.
Kailian HeGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Song XiaoGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Ruiying LiGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Tingjun LiGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Jie XiaoGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Ziqi ChenGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Yulu ChenGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
You LiGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Zhiyong ZhangGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Heath, Department of Environmental Health and Occupational Medicine, School of Public Health, Guilin Medical University, Guilin, China.
Guilin Medical University · CNGuangxi Medical University · CNOcean University of China · CNUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to assess the relationship between the dietary intake of saturated fatty acids (SFAs) and its subtypes (C4:0, C6:0, C8:0, C10:0, C12:0, C14:0, C16:0, and C18:0) and hypertension. Design participants and methods: Adults aged 20 years and older based used the U.S. Health and Nutrition Survey (1999-2018) were used as participants. Two averages of 24 h dietary recall data were obtained for weight-adjusted continuous cross-sectional analysis. Two 24-h recall interview data means were obtained for weight-adjusted continuous cross-sectional analysis. A logistic regression model was used to estimate the weighted odds ratio (OR) and its 95% confidence interval (CI) for hypertension. Results: The study included 7,222 respondents over 20 years of age with a hypertension prevalence of 23.2% and a significant difference in the dietary intake of carbohydrates among patients with hypertension. Dietary intake of nutrients was more in men than in women with hypertension. After adjusting for confounders, adjusting for nutrients, and reducing covariance among nutrients, the OR (95% CI) for women's dietary intake of SFAs, C14:0, C16:0, C18:0 fourth quartile, and C14:0 third quartile were 0.57 (0.34, 0.95), 0.57 (0.34, 0.95), 0.57 (0.34, 0.95), 0.57 (0.34, 0.95), and 0.57 (0.34, 0.95), respectively, which may be a risk factor for hypertension. In older (≥65, years) respondents, the OR (95% CI) for dietary intake of SFAs, C4:0, C14:0, C16:0 fourth quartile, and C12:0 third quartile were 0.42 (0.21, 0.86), 0.46 (0.22, 0.95), 0.39 (0.18, 0.85), 0.38 (0.17, 0.84), and 0.45 (0.20, 0.99), respectively, which may be a protective factor for hypertension. Conclusion: The study was based on the American Health and Nutrition Examination Survey, and a strong correlation was found between dietary intake of SFAs, C14:0, C16:0, and C18:0 and hypertension in women (dietary intake of SFAs, C4:0, C12:0, C14:0, and C16:0) and middle-aged and older adults (dietary intake of SFAs, C4:0, C12:0, C14:0, and C16:0). In addition, dietary nutrient intake should be carefully selected for the rational prevention of hypertension.

Indexed as

cardiovascular diseasedietary saturated fatty acidsdose-responseNHANESsubtype

Identifiers

PMID36407507
PMCPMC9669614
OpenAlexW4308414344

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.