Evidence map›Paper›PMID 36407335›Full record

ReviewAfrican health sciences2022

Why mothers die at a busy tertiary urban hospital in Kampala, Uganda: a comprehensive review of maternal deaths 2016-2018 and implications for quality improvement to reduce deaths.

Imelda Namagembe, Noah Kiwanuka, Josaphat K Byamugisha, Sam Ononge, Jolly Beyeza-Kashesya, Dan K Kaye, Ashley Moffett, Catherine E Aiken, Annettee Nakimuli

Abstract readReview
In one paragraph

Review in African health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Postpartum Cardiovascular Health in African Women Following Pre-Eclampsia: A Prospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025
    Article
  4. Maternal Death: Retrospective Autopsy Study in Southwestern Colombia, 2000-2023.International journal of environmental research and public health · 2025
    Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Editorial.African health sciences · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Imelda NamagembeDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University College of Health Sciences, Uganda, P.O.Box 7072, Kampala, Uganda.
Noah KiwanukaDepartment of Epidemiology and Biostatistics, School of Public Health, Makerere University College of Health Sciences, Uganda, P.O.Box 7072, Kampala, Uganda.
Josaphat K ByamugishaDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University College of Health Sciences, Uganda, P.O.Box 7072, Kampala, Uganda.
Sam OnongeDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University College of Health Sciences, Uganda, P.O.Box 7072, Kampala, Uganda.
Jolly Beyeza-KashesyaDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University College of Health Sciences, Uganda, P.O.Box 7072, Kampala, Uganda.
Dan K KayeDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University College of Health Sciences, Uganda, P.O.Box 7072, Kampala, Uganda.
Ashley MoffettDepartment of Pathology and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom.
Catherine E AikenDepartment of Obstetrics and Gynaecology, University of Cambridge, Box 223, The Rosie Hospital and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 0SW, United Kingdom.
Annettee NakimuliDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University College of Health Sciences, Uganda, P.O.Box 7072, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Reviewing maternal deaths and drawing out lessons for clinical practice is part of an effective cohesive intervention strategy to reduce future deaths. Objective: To review maternal deaths at the National Referral hospital in Kampala over a 3-year period (2016-2018) to determine causes of death, extent of preventability, proportion of deaths notified and audited as per national guidelines. Methods: Trained-multidisciplinary panels (obstetricians and senior midwives) conducted retrospective reviews of maternal deaths that occurred. Results: Major causes of deaths: obstetric haemorrhage (158/350; 45%), hypertensive disorders of pregnancy (87/350; 25%) and infection (95/350; 27%). Overall, 294/350 (84%) of maternal deaths were considered preventable. In 95% (332/350) of cases, delays within healthcare facilities were identified (64%; 226/350). We note that only 115/350 (33%) cases had been audited. This proportion did not change during the studied period. In 48% (167/350) of cases, notification to the Ministry of Health occurred, but only 11% of deaths (39/350) were notified within the recommended 24-hours. Conclusions: A high proportion (84%) of deaths were preventable. Significant delays to care occurred within health-care facilities. Results suggest that a well-supported, and timely maternal death review process with targeted and pragmatic interventions might be effective in reducing maternal deaths in this setting.

Indexed as

Maternal DeathFemaleHospitals, UrbanHumansPregnancyQuality ImprovementRetrospective StudiesUgandadeath-reviewMaternal-deathspreventabilityquality improvement

Identifiers

PMID36407335
PMCPMC9652663

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.