Evidence map›Paper›PMID 36407301›Full record

ArticleFrontiers in endocrinology2022

A 5-year follow-up study on the efficacy and safety of ultrasound-guided laser ablation in elderly patients with papillary thyroid microcarcinoma: A retrospective, single-center study from China.

Zhang Juan, Liang Yongping, Xiaochen Han, Zhiwu Wang, Jingping Liu, Yongfeng Zhao, Wengang Liu, Ping Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Ablative Technologies for Thyroid Nodules: A Health Technology Assessment.Ontario health technology assessment series · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhang JuanDepartment of Breast Surgery, Tangshan People's Hospital, North China University of Science and Technology, Tangshan, China.
Liang YongpingDepartment of Ultrasound, Tangshan People's Hospital, North China University of Science and Technology, Tangshan, China.
Xiaochen HanDepartment of Otolaryngology - Head and Neck, Tangshan People's Hospital, North China University of Science and Technology, Tangshan, China.
Zhiwu WangDepartment of Medical Oncology, Tangshan People's Hospital, North China University of Science and Technology, Tangshan, China.
Jingping LiuDepartment of Ultrasound, Tangshan People's Hospital, North China University of Science and Technology, Tangshan, China.
Yongfeng ZhaoDepartment of Ultrasound, Third Xiangya Hospital, Central South University, Changsha, China.
Wengang LiuDepartment of Ultrasound, Third Xiangya Hospital, Central South University, Changsha, China.
Ping ZhouDepartment of Ultrasound, Third Xiangya Hospital, Central South University, Changsha, China.
Tangshan People's Hospital · CNThird Xiangya Hospital · CNNorth China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study is to evaluate the long-term efficacy and safety of ultrasound-guided percutaneous laser ablation (PLA) for the treatment of elderly patients with papillary thyroid microcarcinoma (PTMC). Methods: From September 2015 to April 2017, 38 elderly patients with PTMC confirmed through fine-needle aspiration biopsy (FNAB) were treated with PLA. Before the treatment, the location and volume of the nodule together with the patients' symptoms were evaluated. Twenty-four hours after the treatment, contrast-enhanced ultrasound (CEUS) was performed to evaluate the completeness of the ablation. To evaluate the volume of the ablation area and recurrence or metastasis, ultrasound examination was performed at 1, 3, 6, and 12 months after the treatment and every 6 months thereafter. FNAB was performed for any suspicious recurrence or metastasis lesions. Result: The ablation of all the 38 patients was all achieved completely as confirmed by CEUS. No obvious complications were found. The success rate of single ablation was 100%. The average follow-up time was 64.58 ± 5.29 months (60-78 months). By the time of the last follow-up, 31 (81.58%) ablation lesions disappeared completely and seven (18.42%) ablation lesions showed scar-like changes. The volume of nodules was 40.69 ± 16.45 mm Conclusion: Ultrasound-guided PLA is effective and safe for the treatment of elderly patients with PTMC who are ineligible for surgery.

Indexed as

Laser TherapyAgedCarcinoma, PapillaryChinaFollow-Up StudiesHumansPolyestersRetrospective StudiesThyroid NeoplasmsUltrasonography, InterventionalPolyesterselderly patientslaser ablationpapillary thyroid microcarcinoma (PTMC)percutaneous thermal ablationultrasound

Identifiers

PMID36407301
PMCPMC9671076
OpenAlexW4308077315

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.