Evidence map›Paper›PMID 36407158›Full record

ArticleCureus2022

Adipose Tissue Grafting for the Treatment of Morphea En Coup De Sabre: A Simple Filler or an Emerging Cellular Therapy?

Mounia El Omari, Malak Debbarh, Mohamed Amine Lakhdari, Zineb Basri, Rita Ait Benhamou

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Mounia El OmariPlastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
Malak DebbarhPlastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
Mohamed Amine LakhdariPlastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
Zineb BasriMedicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
Rita Ait BenhamouPlastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
University of Health SciencesHôpital Universitaire International Cheikh Khalifa · MAInternational University · KH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linear scleroderma en coup de sabre is a rare chronic autoimmune disease. This form of localized scleroderma manifests through an inflammatory phenomenon of collagen overproduction and extracellular matrix destruction, affecting the skin and subcutaneous tissues of the face. This active pathological process is challenging to control and often goes unnoticed at its early stage. The sequelae manifest as an alopecic frontal scar lesion, causing the patient significant aesthetic and psychological damage. In this study, we report two clinical cases in which aesthetic sequelae were treated by autologous fat transplantation. We found encouraging results, with a global aesthetic improvement of 86.2% measured by a jury of medical specialists and outcome stability through a nine-year follow-up for one patient. Autologous fat transfer is excellent for treating stabilized en coup de sabre morphea, not only for its filling abilities but also for its regeneration activating and inflammation regulating abilities, which could open new prospects for curative treatment of this pathology.

Indexed as

adipocytes transplantautologous fat graftingen coup de sabrelipofillingmorpheascleroderma

Identifiers

PMID36407158
PMCPMC9665929
OpenAlexW4306354500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.