Evidence map›Paper›PMID 36407071›Full record

ArticleJMA journal2022

Polyvascular Disease and the Incidence of Cancer in Patients with Coronary Artery Disease.

Makoto Suzuki, Hitonobu Tomoike, Zhehao Dai, Toru Hosoda, Tetsuya Sumiyoshi, Saichi Hosoda, Mitsuaki Isobe

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in JMA journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04198896 (Clinical Aspects of Atherosclerotic-Carcinogenesis Hypothesis), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04198896 completednot on this map

Clinical Aspects of Atherosclerotic-Carcinogenesis Hypothesis

Typeobservational_patient_registrySponsorSakakibara Heart InstituteRan2009 to 2019Enrolled8,856ConditionsCancers, Atheroscleroses, Coronary, Atherosclerosis of ArteryArmsincidece of cancers
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Connecting the Dots: How MicroRNAs Link Asthma and Atherosclerosis.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Makoto SuzukiDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Hitonobu TomoikeDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Zhehao DaiDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Toru HosodaDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Tetsuya SumiyoshiDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Saichi HosodaDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Mitsuaki IsobeDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Sakakibara Hospital · JPToyooka Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Based on the possible relation of atherosclerotic cardiovascular disease to the development of cancer, we examined whether polyvascular disease, as a surrogate marker of the severity of atherosclerosis, is associated with the incidence of cancer in patients with coronary artery disease (CAD). Methods: A total of 8,856 patients with CAD between January 2009 and July 2014 were eligible for this observational study. Two cohorts were established based on the presence or absence of polyvascular disease (i.e., polyvascular disease and CAD only) and tracked for the incidence of cancer and all causes of death. Polyvascular disease was defined when accompanied by diagnosed aortic and/or peripheral arterial disease or other arterial diseases at enrollment. Results: With a median follow-up of 1,095 d, the incidence of cancer was markedly higher in the cohort of 716 patients with polyvascular disease than in the cohort of 8,140 patients with CAD only (8.8% vs. 4.9%, Conclusion: The presence of polyvascular disease may be associated with the incidence of cancer in patients with CAD, implying a pivotal role of the severity of atherosclerosis in cancer development (ClinicalTrials.gov. number: NCT04198896).

Indexed as

atherosclerosiscancercardio-oncologycohort studycoronary artery diseasepolyvascular disease

Identifiers

PMID36407071
PMCPMC9646297
OpenAlexW4309668441

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.