ArticleCyborg and bionic systems (Washington, D.C.)2022
POMDP-Based Real-Time Path Planning for Manipulation of Multiple Microparticles via Optoelectronic Tweezers.
Article in Cyborg and bionic systems (Washington, D.C.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Optoelectronic Tweezers for Single-Cell Research: Principles, Applications, and Prospects.Cyborg and bionic systems (Washington, D.C.) · 2026Review
- Particle-Assisted Optoelectronic Tweezers for Manipulating Single Cells and Microparticles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Automated and collision-free navigation of multiple micro-objects in obstacle-dense microenvironments using optoelectronic tweezers.Microsystems & nanoengineering · 2025Article
- ODEP-Based Robotic System for Micromanipulation and In-Flow Analysis of Primary Cells.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Magnetic Shaftless Propeller Millirobot with Multimodal Motion for Small-Scale Fluidic Manipulation.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Long-Distance Autonomous Navigation of Optical Microrobotic Swarms in Complex Environments.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2024Article
- Green synthesis of copper oxide nanoparticles via Moringa peregrina extract incorporated in graphene oxide: evaluation of antibacterial and anticancer efficacy.Bioprocess and biosystems engineering · 2024Article
- Double-Modal Locomotion of a Hydrogel Ultra-Soft Magnetic Miniature Robot with Switchable Forms.Cyborg and bionic systems (Washington, D.C.) · 2024Article
- Active Micro/Nanoparticles in Colloidal Microswarms.Nanomaterials (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With high throughput and high flexibility, optoelectronic tweezers (OETs) hold huge potential for massively parallel micromanipulation. However, the trajectory of the virtual electrode has been planned in advance in most synchronous manipulations for multiple targets based on an optically induced dielectrophoresis (ODEP) mechanism, which is insufficient to ensure the stability and efficiency in an environment with potential collision risk. In this paper, a synchronously discretized manipulation method based on a centralized and decoupled path planner is proposed for transporting microparticles of different types with an OET platform. An approach based on the Kuhn-Munkres algorithm is utilized to achieve the goal assignment between target microparticles and goal positions. With the assistance of a visual feedback module, a path planning approach based on the POMDP algorithm dynamically determines the motion strategies of the particle movement to avoid potential collisions. The geometrical parameters of the virtual electrodes are optimized for different types of particles with the goal of maximum transport speed. The experiments of micropatterning with different morphologies and transporting multiple microparticles (e.g., polystyrene microspheres and 3T3 cells) to goal positions are performed. These results demonstrate that the proposed manipulation method based on optoelectronic tweezers is effective for multicell transport and promises to be used in biomedical manipulation tasks with high flexibility and efficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.