Evidence map›Paper›PMID 36406889›Full record

ReviewFrontiers in reproductive health2022

Which vaginal douching agent is the best choice before oocyte retrieval? A systematic review and network meta-analysis.

Ying Meng, Gui H Wen, Hong Luo, Xiu C Tan, Li Wang, Juan Liao, Hong Peng, Ling Lan, Na Yang, Ying Zhao

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in reproductive health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. A case report of female vaginal myiasis.Annals of medicine and surgery (2012) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ying MengCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Gui H WenCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Hong LuoCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Xiu C TanCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Li WangCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Juan LiaoCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Hong PengCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Ling LanCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Na YangCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Ying ZhaoCenter for Reproductive Medicine, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNChildren's Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to evaluate six vaginal douching agents (Iodine, Saline, Iodine followed by saline, chlorhexidine acetate followed by saline, Ozone, Potassium permanganate) on oocytes pick-up related pelvic infection (OPU-PI) and IVF outcome in patients underwent assisted reproduction technology (ART). Design: Through searching PubMed, Embase, Cochrane Library, Web of Science, Ovid, CINAHL CNKI, only human clinical trials were collected to study the effects of the six vaginal douching agents on OPU-PI and IVF outcomes. The included studies were evaluated for methodological quality by the Cochrane bias risk assessment tool, and the data analysis software was used to analyze the data accordingly. Results: The clinical trials were collected between the earliest available date and June 2022. Eight studies were included, the total sample size used in the study was 12,567. The results of the network meta-analysis showed that Ozone can significantly decrease OPU-PI; Iodine followed by saline can be a antiseptic protocol ranked first without affecting the quality of oocytes and Chlorhexidine acetate followed by saline can improve patients' clinical pregnancy rate. Conclusion: Based on Ranking Plot of the Network, this review reports the best evidence available regarding different vaginal douching agents used before OPU.

Indexed as

IVF outcomenetwork meta analysisoocyte retrievalpelvic infectionvaginal douching

Identifiers

PMID36406889
PMCPMC9672680
OpenAlexW4308334518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.