Evidence map›Paper›PMID 36406780›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2022

Outcomes After Liver Transplantation With Incidental Cholangiocarcinoma.

Nawaz Z Safdar, Abdul R Hakeem, Rosemary Faulkes, Fiona James, Lisa Mason, Steven Masson, James Powell, Ian Rowe, Shishir Shetty, Rebecca Jones and 6 more

Open access · goldAbstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Nawaz Z SafdarSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Abdul R HakeemLeeds Liver Unit, St James' University Hospital, Leeds, United Kingdom.
Rosemary FaulkesUniversity Hospitals Birmingham, Birmingham, United Kingdom.
Fiona JamesLeeds Liver Unit, St James' University Hospital, Leeds, United Kingdom.
Lisa MasonRoyal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Steven MassonNewcastle Upon Tyne Hospitals, Newcastle, United Kingdom.
James PowellRoyal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Ian RoweLeeds Liver Unit, St James' University Hospital, Leeds, United Kingdom.
Shishir ShettyUniversity Hospitals Birmingham, Birmingham, United Kingdom.
Rebecca JonesLeeds Liver Unit, St James' University Hospital, Leeds, United Kingdom.
Harry V M SpiersRoy Calne Transplant Unit, Addenbrooke's Hospital, Cambridge, United Kingdom.
Neil HallidayThe Royal Free, London, United Kingdom.
Jack BakerThe Royal Free, London, United Kingdom.
Douglas ThorburnThe Royal Free, London, United Kingdom.
Raj PrasadLeeds Liver Unit, St James' University Hospital, Leeds, United Kingdom.
Richard ParkerLeeds Liver Unit, St James' University Hospital, Leeds, United Kingdom.
Edinburgh Royal Infirmary · GBNIHR Surgical Reconstruction and Microbiology Research Centre · GBThe Royal Free Hospital · GBNewcastle upon Tyne Hospital · GBNHS Blood and Transplant · GBUniversity College London · GBUniversity of Leeds · GB

Funding

Medical Research Council MR/V029843/1
6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) is currently a contraindication to liver transplantation (LT) in the United Kingdom (UK). Incidental CCA occurs rarely in some patients undergoing LT. We report on retrospective outcomes of patients with incidental CCA from six UK LT centres. Cases were identified from pathology records. Data regarding tumour characteristics and post-transplant survival were collected. CCA was classified by TNM staging and anatomical location. 95 patients who underwent LT between 1988-2020 were identified. Median follow-up after LT was 2.1 years (14 days-18.6 years). Most patients were male (68.4%), median age at LT was 53 (IQR 46-62), and the majority had underlying PSC (61%). Overall median survival after LT was 4.4 years. Survival differed by tumour site: 1-, 3-, and 5-year estimated survival was 82.1%, 68.7%, and 57.1%, respectively, in intrahepatic CCA (

Indexed as

Bile Duct NeoplasmsCholangiocarcinomaLiver TransplantationArachnodactylyBile Ducts, IntrahepaticContractureFemaleHumansMaleRetrospective Studiesdistalhepatocellularhilarindicationintrahepaticsurvivaltransplanttumor

Identifiers

PMID36406780
PMCPMC9667791
OpenAlexW4308120707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.